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Frontal cortex activity during the production of diverse social communication calls in marmoset monkeys
In nonhuman primates, the role of frontal cortex in vocal production is unclear. Using wireless recording techniques in marmosets in a naturalistic social context, here the authors show that frontal cortex neural signals show distinct patterns for different call types.
- Lingyun Zhao
- & Xiaoqin Wang
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Initial conditions combine with sensory evidence to induce decision-related dynamics in premotor cortex
It remains unclear why some decisions take longer than others even when the sensory inputs are similar. Here, the authors show that both initial neural state and sensory input combine in the premotor cortex to influence the speed and geometry of neural population activity during decisions.
- Pierre O. Boucher
- , Tian Wang
- & Chandramouli Chandrasekaran
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Conserved structures of neural activity in sensorimotor cortex of freely moving rats allow cross-subject decoding
Conservation of the neural code across subjects is crucial for training brain-computer interfaces. Through alignment of neural manifolds, the authors show cross-subject generalization in the decoding of unconstrained behavior from sensorimotor cortex.
- Svenja Melbaum
- , Eleonora Russo
- & Ilka Diester
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Distinct dynamics of neuronal activity during concurrent motor planning and execution
Animal behaviour is governed by planning and executing movements. Here, using non-stereotypical movements to separate planning and executional processes, the authors find evidence for slow processes for planning and fast processes for movement execution.
- David Eriksson
- , Mona Heiland
- & Ilka Diester
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Article
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Direct electrical stimulation of the premotor cortex shuts down awareness of voluntary actions
Here, using electrical stimulation on patients undergoing awake brain surgery, the authors show that disruption of the premotor cortex makes patients unconscious of motor arrest. This finding suggests the premotor cortex is crucial for motor awareness.
- Luca Fornia
- , Guglielmo Puglisi
- & Francesca Garbarini
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Simultaneous motor preparation and execution in a last-moment reach correction task
Motor preparation processes guide movement. Here, by recording neural activity in monkeys reaching toward targets that can change location, the authors provide evidence that changing a prepared movement midway through completion reengages motor preparation.
- K. Cora Ames
- , Stephen I. Ryu
- & Krishna V. Shenoy
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Macaque dorsal premotor cortex exhibits decision-related activity only when specific stimulus–response associations are known
It is not clear to what degree activity in dorsal premotor cortex (PMd) reflects perceptual-deliberation versus action-selection aspects of decision-making. Here, the authors report that monkey PMd neurons do not express correlates of the perceptual decision independently of the action choices.
- Megan Wang
- , Christéva Montanède
- & John F. Kalaska
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An orderly single-trial organization of population dynamics in premotor cortex predicts behavioral variability
To explain the neural correlates of behavior and its variability, one must analyze single-trial population dynamics. Here, the authors develop a statistical method that extracts low-dimensional dynamics that explain behavior better than high-dimensional neural activity revealing unexpected structure.
- Ziqiang Wei
- , Hidehiko Inagaki
- & Shaul Druckmann
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Single reach plans in dorsal premotor cortex during a two-target task
It is debated whether motor cortical activity reflects plans for multiple potential actions. Here, the authors report that in a delayed response task with two potential reach targets, population activity in the dorsal premotor cortex at any moment in time represents only one of the targets.
- Brian M. Dekleva
- , Konrad P. Kording
- & Lee E. Miller
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Different population dynamics in the supplementary motor area and motor cortex during reaching
Population activity dynamics underlie many neural computations. Here the authors develop a novel hypothesis-guided dimensionality reduction approach that reveals very different population dynamics in the SMA and M1, despite superficially similar single-neuron responses.
- A. H. Lara
- , J. P. Cunningham
- & M. M. Churchland
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Population coding of conditional probability distributions in dorsal premotor cortex
Movements are continually constrained by the current body position and its relation to the surroundings. Here the authors report that the population activity of monkey dorsal premotor cortex neurons dynamically represents the probability distribution of possible reach directions.
- Joshua I. Glaser
- , Matthew G. Perich
- & Konrad P. Kording
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Laminar differences in decision-related neural activity in dorsal premotor cortex
Dorsal premotor cortex (PMd) is thought to be involved in making somatomotor decisions. Chandrasekaran et al. investigated the temporal response dynamics of PMd neurons across cortical layers and show stronger and earlier decision-related responses in the superficial layers and more action execution-related signals in the deeper layers.
- Chandramouli Chandrasekaran
- , Diogo Peixoto
- & Krishna V. Shenoy
Superior colliculus bidirectionally modulates choice activity in frontal cortex