Post-traumatic stress disorder articles from across Nature Portfolio

Neurostimulation has been proposed as a potential approach for treatment-resistant PTSD. Here in a pilot study the authors show that amygdala theta activity is heightened during aversive and symptomatic experiences in patients with treatment-resistant post-traumatic stress disorder, and reduced following significant clinical improvement associated with closed-loop stimulation.

Using machine learning, Zhang et al. identify EEG signature to predict psychotherapy outcomes in PTSD, paving the way towards the development of scalable biomarkers.

In this prospective cohort study of Syrian refugee children living in Lebanon, authors identified that daily exposure to stressors was the factor most strongly associated with children’s mental health problems.