Polyploidy articles from across Nature Portfolio

Domesticated industrial yeast strains are sterile, which hampers to breed strains with novel properties. Here, the authors employ the genetics paradigm return-to-growth to induce genome wide recombination in two sterile polyploid industrial yeasts and identify clones with superior biotechnological traits.

Extensive DNA damage occurs during the first interphase following induction of tetraploidy in human cells, largely as a result of the lower amount of protein relative to DNA.

Arabidopsis suecica is an allotetraploid derived from Arabidopsis thaliana and Arabidopsis arenosa. Analysis of resynthesized and natural allotetraploid A. suecica shows balanced genomic variation accompanied by convergent and concerted changes in DNA methylation and gene expression between two subgenomes that probably contributed to genome stability during polyploid evolution.