News & Views |
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News & Views |
Unification through disarray
High-resolution imaging, composition analysis and mechanical testing reveal a disordered transitional material within the Achilles tendon-to-bone attachment, structured as a fibrous network to enable force transfer and maximize structural integrity.
- Guy M. Genin
- & Stavros Thomopoulos
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News & Views |
Conscripted by collagen
In atherosclerotic plaques, patterns of calcification — which have profound implications for plaque stability and vulnerability to rupture — are determined by the collagen's content and patterning throughout the plaque.
- Jordan D. Miller
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Article |
A magnetic protein biocompass
A polymeric protein complex consisting of a newly identified magnetoreceptor protein and known magnetoreception-related photoreceptor cryptochromes exhibits spontaneous alignment in magnetic fields.
- Siying Qin
- , Hang Yin
- & Can Xie
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News & Views |
Water brings order
Measurements of the structure and organization of intact bone samples show that water plays a significant role in orienting bone apatite crystals, and that such ordering is mediated by an amorphous mineral coating layer.
- Melinda Duer
- & Arthur Veis
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News & Views |
Orbicular origins
The application of imaging techniques prevalent in materials science to the biological process of soft tissue calcification lends new insight into age-related cardiovascular disease.
- Jordan D. Miller
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Article |
The predominant role of collagen in the nucleation, growth, structure and orientation of bone apatite
Calcium-rich non-collagenous proteins in the extracellular matrix of bone are believed to be involved in the different steps of bone mineralization. It is now shown that in the absence of these proteins collagen can initiate and orient growing apatite crystals in vitro, and influence both their structural characteristics on the atomic scale and their larger-scale three-dimensional distribution in bone.
- Yan Wang
- , Thierry Azaïs
- & Nadine Nassif