Physical sciences

Definition

Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature - often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics.

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Latest Research and Reviews

  • Research | | open

    Redox processes in metal oxide surfaces can exhibit structure sensitivities which are difficult to uncover. Here, the authors use atomic-resolution imaging to demonstrate facet dependent alterations in the surfaces of supported vanadium oxide upon reduction and oxidation.

    • Martin Ek
    • , Quentin M. Ramasse
    • , Logi Arnarson
    • , Poul Georg Moses
    •  & Stig Helveg
  • Research | | open

    Metal/oxide interfaces play an important role in heterogeneous catalysis and redox reactions, but their buried nature makes them difficult to study. Here, the authors use environmental transmission electron microscopy to probe the atomic-level transformations at Cu2O/Cu interfaces as they undergo redox reactions.

    • Lianfeng Zou
    • , Jonathan Li
    • , Dmitri Zakharov
    • , Eric A. Stach
    •  & Guangwen Zhou
  • Research | | open

    SWATH-mass spectrometry consists of a data-independent acquisition and a targeted data analysis strategy that aims to maintain the favorable quantitative characteristics on the scale of thousands of proteins. Here, using data generated by eleven groups worldwide, the authors show that SWATH-MS is capable of generating highly reproducible data across different laboratories.

    • Ben C. Collins
    • , Christie L. Hunter
    • , Yansheng Liu
    • , Birgit Schilling
    • , George Rosenberger
    • , Samuel L. Bader
    • , Daniel W. Chan
    • , Bradford W. Gibson
    • , Anne-Claude Gingras
    • , Jason M. Held
    • , Mio Hirayama-Kurogi
    • , Guixue Hou
    • , Christoph Krisp
    • , Brett Larsen
    • , Liang Lin
    • , Siqi Liu
    • , Mark P. Molloy
    • , Robert L. Moritz
    • , Sumio Ohtsuki
    • , Ralph Schlapbach
    • , Nathalie Selevsek
    • , Stefani N. Thomas
    • , Shin-Cheng Tzeng
    • , Hui Zhang
    •  & Ruedi Aebersold
  • Research | | open

    Our incomplete understanding of how pancreatic beta cells form limits the generation of beta-like cells from human pluripotent stem cells (hPSC). Here, the authors identify a ROCKII inhibitor H1152 as increasing insulin secreting cells from hPSCs and improving beta-cell maturation on transplantation in vivo.

    • Zaniar Ghazizadeh
    • , Der-I Kao
    • , Sadaf Amin
    • , Brandoch Cook
    • , Sahana Rao
    • , Ting Zhou
    • , Tuo Zhang
    • , Zhaoying Xiang
    • , Reyn Kenyon
    • , Omer Kaymakcalan
    • , Chengyang Liu
    • , Todd Evans
    •  & Shuibing Chen
  • Research | | open

    Mapping the sequence specificity of DNA ligands remains a challenge, particularly for small drugs. Here the authors develop a parallelized single molecule magnetic tweezers approach using engineered DNA hairpins that can detect sequence selectivity, thermodynamics and kinetics of binding for small drugs and large proteins.

    • Maria Manosas
    • , Joan Camunas-Soler
    • , Vincent Croquette
    •  & Felix Ritort

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