Personalized medicine

Definition

Personalized medicine is a therapeutic approach involving the use of an individual’s genetic and epigenetic information to tailor drug therapy or preventive care.

Latest Research and Reviews

News and Comment

  • Comments and Opinion |

    • Ava C Carter
    • , Howard Y Chang
    • , George Church
    • , Ashley Dombkowski
    • , Joseph R Ecker
    • , Elad Gil
    • , Paul G Giresi
    • , Henry Greely
    • , William J Greenleaf
    • , Nir Hacohen
    • , Chuan He
    • , David Hill
    • , Justin Ko
    • , Isaac Kohane
    • , Anshul Kundaje
    • , Megan Palmer
    • , Michael P Snyder
    • , Joyce Tung
    • , Alexander Urban
    • , Marc Vidal
    •  & Wing Wong
    Nature Biotechnology 35, 1128–1132
  • Comments and Opinion |

    The availability of targeted anticancer drugs and the relative affordability of genomic analyses has led to a growing expectation among patients with cancer that they can receive personalized treatment based on the genomic signature of their tumour. Here, we discuss some of the challenges and steps needed to bring such approaches into routine practice.

    • Roberto Salgado
    • , Helen Moore
    • , John W. M. Martens
    • , Tracy Lively
    • , Shakun Malik
    • , Ultan McDermott
    • , Stefan Michiels
    • , Jeffrey A. Moscow
    • , Sabine Tejpar
    • , Tawnya McKee
    • , Denis Lacombe
    •  & on behalf of the IBCD-Faculty
  • Comments and Opinion |

    Eric D. Green, Edward M. Rubin and Maynard V. Olson speculate on the next forty years of the applications, from policing to data storage.

  • Comments and Opinion |

    Technological advances are creating an explosion in possibilities for the blood-based diagnosis of brain injuries, infections and cancers.

    • Emily Sohn
    Nature 549, S16–S18