Peptide nucleic acid oligo

Peptide nucleic acids are synthetic polymers that mimic the structure of DNA or RNA. PNAs are used in various molecular biology techniques involving specific recognition of a complementary DNA or RNA strand and have been investigated as the basis for diagnostics and antisense therapies.

Latest Research and Reviews

News and Comment

  • News & Views |

    Findeisen et al. have engineered IC7Fc, a cytokine for the treatment of type 2 diabetes, that selectively activates beneficial metabolic pathways systemically and in metabolic tissues without promoting an inflammatory response.

    • Marc Y. Donath
    Nature Metabolism 1, 933-934
  • News & Views |

    Oligonucleotides with unnatural sugar backbones that can be replicated in vitro may open up new avenues for synthetic biology and beyond.

    • Fintan R Steele
    •  & Larry Gold
    Nature Biotechnology 30, 624-625
  • News & Views |

    A process in which peptide nucleic acids may be used for in vitro evolution has been developed. This method can offer enormous opportunities to evolve stable, non-natural molecules for therapeutic applications.

    • Daniel H Appella