Parasitic infection

Definition

Parasitic infection describes the infection of a host with a particular parasite. Parasites are microorganisms that rely on other host organisms for their own survival. Many parasites do not cause any harm to their host, but some parasitic infections cause severe diseases, such as malaria.

Latest Research and Reviews

  • Research |

    Yarovinsky and colleagues identify the alarmin S100A11, which is released from Toxoplasma gondii–infected cells, as the trigger for immune responses in humans. S100A11 induces expression of the chemokine CCL2, which recruits inflammatory CCR2+ monocytes to the sites of infection.

    • Alexandra Safronova
    • , Alessandra Araujo
    • , Ellie T. Camanzo
    • , Taylor J. Moon
    • , Michael R. Elliott
    • , Daniel P. Beiting
    •  & Felix Yarovinsky
    Nature Immunology 20, 64–72
  • Research | | open

    Comparative study of 81 genomes of parasitic and non-parasitic worms identifies gene family births and expanded gene families at key nodes in the phylogeny that are relevant to parasitism and proteins historically targeted for drug development.

    • Avril Coghlan
    • , Rahul Tyagi
    • , James A. Cotton
    • , Nancy Holroyd
    • , Bruce A. Rosa
    • , Isheng Jason Tsai
    • , Dominik R. Laetsch
    • , Robin N. Beech
    • , Tim A. Day
    • , Kymberlie Hallsworth-Pepin
    • , Huei-Mien Ke
    • , Tzu-Hao Kuo
    • , Tracy J. Lee
    • , John Martin
    • , Rick M. Maizels
    • , Prudence Mutowo
    • , Philip Ozersky
    • , John Parkinson
    • , Adam J. Reid
    • , Neil D. Rawlings
    • , Diogo M. Ribeiro
    • , Lakshmipuram Seshadri Swapna
    • , Eleanor Stanley
    • , David W. Taylor
    • , Nicolas J. Wheeler
    • , Mostafa Zamanian
    • , Xu Zhang
    • , Fiona Allan
    • , Judith E. Allen
    • , Kazuhito Asano
    • , Simon A. Babayan
    • , Germanus Bah
    • , Helen Beasley
    • , Hayley M. Bennett
    • , Stewart A. Bisset
    • , Estela Castillo
    • , Joseph Cook
    • , Philip J. Cooper
    • , Teresa Cruz-Bustos
    • , Carmen Cuéllar
    • , Eileen Devaney
    • , Stephen R. Doyle
    • , Mark L. Eberhard
    • , Aidan Emery
    • , Keeseon S. Eom
    • , John S. Gilleard
    • , Daria Gordon
    • , Yvonne Harcus
    • , Bhavana Harsha
    • , John M. Hawdon
    • , Dolores E. Hill
    • , Jane Hodgkinson
    • , Petr Horák
    • , Kevin L. Howe
    • , Thomas Huckvale
    • , Martin Kalbe
    • , Gaganjot Kaur
    • , Taisei Kikuchi
    • , Georgios Koutsovoulos
    • , Sujai Kumar
    • , Andrew R. Leach
    • , Jane Lomax
    • , Benjamin Makepeace
    • , Jacqueline B. Matthews
    • , Antonio Muro
    • , Noel Michael O’Boyle
    • , Peter D. Olson
    • , Antonio Osuna
    • , Felix Partono
    • , Kenneth Pfarr
    • , Gabriel Rinaldi
    • , Pilar Foronda
    • , David Rollinson
    • , Mercedes Gomez Samblas
    • , Hiroshi Sato
    • , Manuela Schnyder
    • , Tomáš Scholz
    • , Myriam Shafie
    • , Vincent N. Tanya
    • , Rafael Toledo
    • , Alan Tracey
    • , Joseph F. Urban
    • , Lian-Chen Wang
    • , Dante Zarlenga
    • , Mark L. Blaxter
    • , Makedonka Mitreva
    •  & Matthew Berriman
  • Research | | open

    Parasitic helminth infection is known to impact upon the host response to other bystander inflammatory processes. Here the authors show that IL4 production induced by helminth infection results in expansion of bystander CD8+ memory T cells and enhanced control to viral infection.

    • Marion Rolot
    • , Annette M. Dougall
    • , Alisha Chetty
    • , Justine Javaux
    • , Ting Chen
    • , Xue Xiao
    • , Bénédicte Machiels
    • , Murray E. Selkirk
    • , Rick M. Maizels
    • , Cornelis Hokke
    • , Olivier Denis
    • , Frank Brombacher
    • , Alain Vanderplasschen
    • , Laurent Gillet
    • , William G. C. Horsnell
    •  & Benjamin G. Dewals
  • Research | | open

    The decision when to stop an intervention is a critical component of parasite elimination programmes, but reliance on surveillance data alone can be inaccurate. Here, Michael et al. combine parasite transmission model predictions with disease survey data to more reliably determine when interventions can be stopped.

    • Edwin Michael
    • , Morgan E. Smith
    • , Moses N. Katabarwa
    • , Edson Byamukama
    • , Emily Griswold
    • , Peace Habomugisha
    • , Thomson Lakwo
    • , Edridah Tukahebwa
    • , Emmanuel S. Miri
    • , Abel Eigege
    • , Evelyn Ngige
    • , Thomas R. Unnasch
    •  & Frank O. Richards

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