Parasite genetics articles from across Nature Portfolio

The ability to evolve Plasmodium drug resistance in vitro is challenging and time consuming. Here, Kümpornsin et al. generated a Plasmodium falciparum parasite line with an elevated mutation rate by impairing the proof-reading activity of DNA polymerase, which results in a higher mutation rate, quick resistance development, and a lower inoculum than wild type to support the identification of new antimalarial targets and understand drug resistance mechanisms.

Chloroquine resistance in Plasmodium falciparum is characterized using population genomics, genetic crosses and gene editing.

This month’s Genome Watch highlights recent advances in genome editing of parasitic worms that affect one-fifth of humans globally.

A new study shows that antisense long noncoding RNAs contribute tovar gene activation in Plasmodium falciparum.

A new study identifies the mechanistic basis for host cell transformation byTheileriaspp. parasites.