Osteopetrosis articles within Nature Communications

Featured

• Article
  21 February 2023 | Open Access

  Sugar transporter Slc37a2 regulates bone metabolism in mice via a tubular lysosomal network in osteoclasts

  Despite the importance of osteoclast secretory lysosomes in bone digestion, the proteins that regulate them remain ill defined. Here, the authors identify Slc37a2 as a secretory lysosome sugar transporter that is required for maintenance of skeletal bone mass.

  • Pei Ying Ng
  • , Amy B. P. Ribet
  •  & Nathan J. Pavlos

• Article
  16 September 2021 | Open Access

  Automated bone mineral density prediction and fracture risk assessment using plain radiographs via deep learning

  Dual-energy X-ray absorptiometry and the Fracture Risk Assessment Tool are recommended tools for osteoporotic fracture risk evaluation, but are underutilized. Here, the authors present an opportunistic tool to identify fractures, predict bone mineral density and evaluate fracture risk using plain pelvis and lumbar spine radiographs.

  • Chen-I Hsieh
  • , Kang Zheng
  •  & Chang-Fu Kuo