Featured
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| Open AccessMultipole engineering by displacement resonance: a new degree of freedom of Mie resonance
Mie resonances are typically manipulated through varying nanostructure shape/size. Here, authors found that Gaussian beam displacement excites higher-order multipolar modes, not accessible by plane wave, featuring maximal linear and nonlinear scattering efficiency when the focus is misaligned.
- Yu-Lung Tang
- , Te-Hsin Yen
- & Shi-Wei Chu
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Article
| Open AccessAccessible hotspots for single-protein SERS in DNA-origami assembled gold nanorod dimers with tip-to-tip alignment
The identification of individual proteins is highly desirable in diagnostics. Here, the authors report on DNA-origami assembled dimers of gold nanorod with accessible hotspots to capture and identify single proteins from solution by SERS.
- Francis Schuknecht
- , Karol Kołątaj
- & Theobald Lohmueller
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Article
| Open AccessDisordered metasurface enabled single-shot full-Stokes polarization imaging leveraging weak dichroism
Polarization imaging can capture information from the scene that cannot directly be recorded by traditional intensity cameras. Here, authors demonstrate a single-shot full Stokes polarization camera incorporating a disordered metasurface array with weak dichroism.
- Qingbin Fan
- , Weizhu Xu
- & Ting Xu
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Article
| Open AccessTraining large-scale optoelectronic neural networks with dual-neuron optical-artificial learning
Optoelectronic neural networks are a promising avenue in AI computing for parallelization, power efficiency, and speed. Here, the authors present a dual-neuron optical-artificial learning approach for training large-scale diffractive neural networks, achieving VGG-level performance on ImageNet in simulation with a network that is 10 times larger than existing ones.
- Xiaoyun Yuan
- , Yong Wang
- & Lu Fang
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Article
| Open AccessEfficient optical plasmonic tweezer-controlled single-molecule SERS characterization of pH-dependent amylin species in aqueous milieus
Studying rare species in mixtures is challenging. Here, authors utilize on-and-off optical plasmonic trapping to control SERS-active nanocavity to analyse pH-dependent amylin species at single-molecule level, unveiling amyloid aggregation mechanisms.
- Wenhao Fu
- , Huanyu Chi
- & Jinqing Huang
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Article
| Open AccessMetasurface-empowered snapshot hyperspectral imaging with convex/deep (CODE) small-data learning theory
Hyperspectral imagers play a vital role in material identification, but traditionally, they have been bulky. Here, the authors introduce a compact hyperspectral imaging system that combines metasurface optics with small-data deep learning.
- Chia-Hsiang Lin
- , Shih-Hsiu Huang
- & Pin Chieh Wu
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Article
| Open AccessTracing multiple scattering trajectories for deep optical imaging in scattering media
Deep imaging in complex scattering media is hindered by multiple light scattering. Here, the authors proposed a method to trace multiple scattering trajectories in situ using a recorded reflection matrix and achieved enhanced imaging depth by converting these multiple scattering to signal waves.
- Sungsam Kang
- , Yongwoo Kwon
- & Wonshik Choi
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Article
| Open AccessPolarization structured light 3D depth image sensor for scenes with reflective surfaces
Highly reflective surfaces are notorious in 3D sensing because they can cause errors in depth perception. Here, the authors devise a polarization structured light 3D sensor for this problem, in which high-contrast-grating VCSELs are used. Experiments are reported to demonstrate the sensor can be used to see and see through the highly reflective surfaces.
- Xuanlun Huang
- , Chenyang Wu
- & Connie J. Chang-Hasnain
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Article
| Open AccessRheological engineering of perovskite suspension toward high-resolution X-ray flat-panel detector
The film uniformity is essential to the fixed pattern noise (FPN) and resolution of X-ray detectors. Here the authors demonstrate the rheological engineering of the perovskite suspension to achieve low FPN of 1.39% and high resolution of 0.51 lp/pix.
- Zihao Song
- , Xinyuan Du
- & Jiang Tang
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Article
| Open AccessLearning diffractive optical communication around arbitrary opaque occlusions
Researchers demonstrate robust optical communication around fully opaque occlusions, partially or entirely blocking the light path, using a pair of electronic encoder and passive diffractive decoder that are jointly optimized using deep learning.
- Md Sadman Sakib Rahman
- , Tianyi Gan
- & Aydogan Ozcan
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Article
| Open AccessRapid sensing of hidden objects and defects using a single-pixel diffractive terahertz sensor
Researchers showcase a deep learning-designed diffractive terahertz sensor that rapidly detects hidden defects within 3D samples based on the output spectrum measured by a single-pixel detector, eliminating sample scanning or image formation/processing.
- Jingxi Li
- , Xurong Li
- & Aydogan Ozcan
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Article
| Open AccessSingle virus fingerprinting by widefield interferometric defocus-enhanced mid-infrared photothermal microscopy
The study of viruses relies on the detection of viral proteins or viral nucleic acids. Here, the authors present a widefield interferometric defocus-enhanced mid-infrared photothermal (WIDE-MIP) microscope for high-throughput fingerprinting of single viruses.
- Qing Xia
- , Zhongyue Guo
- & Ji-Xin Cheng
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Article
| Open AccessSubwavelength terahertz imaging via virtual superlensing in the radiating near field
The authors develop a method for sub-diffraction near-field imaging using measurements taken relatively far from an object, amplifying evanescent waves that encode the highest resolution. The increased distance greatly reduces the perturbation of the fields by the imaging device itself.
- Alessandro Tuniz
- & Boris T. Kuhlmey
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Article
| Open AccessCreating tunable lateral optical forces through multipolar interplay in single nanowires
It is a significant challenge to create an interface-free lateral optical force under the illumination of a single polarized plane wave. Here, the authors provide a minimalist paradigm to address this challenge by exploiting multipolar interplay in a single elongated particle.
- Fan Nan
- , Francisco J. Rodríguez-Fortuño
- & Xiaohao Xu
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Article
| Open AccessIntegrated reconstructive spectrometer with programmable photonic circuits
Recent years have seen a growing need for miniaturized spectroscopic tools. Here, authors present a novel integrated spectrometer with programmable photonic circuits, achieving record-high resolution and bandwidth via only a few filtering components.
- Chunhui Yao
- , Kangning Xu
- & Richard Penty
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Article
| Open AccessIn vivo noninvasive systemic myography of acute systemic vasoactivity in female pregnant mice
The assessment of selective therapeutics targeted to treat altered vasoactivity, a major characteristic of cardiovascular and oncological diseases, is still challenging due to unknown whole-body selectivity. Here the authors demonstrate that photoacoustic tomography has the potential to capture significant acute vasodilation of major arteries and vasculature selectivity.
- Kristie Huda
- , Dylan J. Lawrence
- & Carolyn L. Bayer
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Article
| Open AccessVisualizing moiré ferroelectricity via plasmons and nano-photocurrent in graphene/twisted-WSe2 structures
Recent experiments have shown the formation of ferroelectric domains in twisted van der Waals bilayers. Here, the authors report near-field infrared nano-imaging and nano-photocurrent measurements to investigate ferroelectricity in minimally twisted WSe2 by visualizing the plasmonic and photo-thermoelectric response of an adjacent graphene monolayer.
- Shuai Zhang
- , Yang Liu
- & D. N. Basov
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Article
| Open AccessOrientation distributions of vacuum-deposited organic emitters revealed by single-molecule microscopy
The understanding of the orientation of luminescent molecules is currently limited by the ensemble-averaging nature of state-of-the-art measurements. Here, the authors apply single-molecule imaging to obtain complete orientation distributions of the transition dipole of individual emitter molecules.
- Francisco Tenopala-Carmona
- , Dirk Hertel
- & Malte C. Gather
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Article
| Open AccessHigh-resolution single-photon imaging with physics-informed deep learning
High-resolution single-photon imaging is challenging due to complex hardware and noise disturbances. Here, the authors realise simultaneous single-photon denoising and super-resolution enhancement by physics-informed deep learning, with a physical multi-source noise model, two single-photon image datasets, and a deep transformer network.
- Liheng Bian
- , Haoze Song
- & Jun Zhang
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| Open AccessIntrinsic 1\({T}^{{\prime} }\) phase induced in atomically thin 2H-MoTe2 by a single terahertz pulse
A single field-enhanced terahertz pulse was used to create 1\({T}^{{\prime} }\)-MoTe2 out of few-layer H-MoTe2 crystals, providing insights into the ultrafast polymorphic transition dynamics and resolving a long-standing debate over the realization of this transition by high-energy photon irradiation.
- Jiaojian Shi
- , Ya-Qing Bie
- & Keith A. Nelson
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Article
| Open AccessAn entropy-controlled objective chip for reflective confocal microscopy with subdiffraction-limit resolution
The optimized and disordered structures of planar diffractive lenses enable sub-diffraction limit focusing but destroy wide-field imaging. Here, the authors introduce the information entropy to evaluate the disorder of PDL and achieve good balance between super-focusing and imaging.
- Jun He
- , Dong Zhao
- & Kun Huang
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Article
| Open AccessLight-enhanced molecular polarity enabling multispectral color-cognitive memristor for neuromorphic visual system
Designing optoelectronic synapses having a multispectral color-discriminating ability is crucial for neuromorphic visual system. Here, the authors propose an strategy to introduce RGB color-discriminating synaptic functionality into a 2-terminals memristor regardless of switching medium and design a color image-recognizing CNN and light-programmable reservoir computing.
- Jongmin Lee
- , Bum Ho Jeong
- & Hui Joon Park
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Article
| Open AccessRobotic-OCT guided inspection and microsurgery of monolithic storage devices
Demand for data recovery from monolithic storage devices is high but current methods are inefficient. Here, authors develop a robotic OCT-guided inspection and microsurgery method, minimizing damage to device and enhancing data recovery efficiency.
- Bin He
- , Yuxin Zhang
- & Ning Zhang
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Article
| Open AccessOptimized virtual optical waveguides enhance light throughput in scattering media
Virtual optical waveguide can be potentially utilised in variety of applications that require in situ light steering yet the efficacy is still unclear. Here, the authors show that ultrasonically-sculpted virtual gradient-index waveguides are effective in guiding and confining light inside tissue and other scattering media, and significantly outperform external lenses at this task.
- Adithya Pediredla
- , Matteo Giuseppe Scopelliti
- & Ioannis Gkioulekas
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Article
| Open AccessDemonstration of an AI-driven workflow for autonomous high-resolution scanning microscopy
Modern microscopes can image a sample with sub-Angstrom and sub-picosecond resolutions, but this often requires analysis of tremendously large datasets. Here, the authors demonstrate that an autonomous experiment can yield over a 70% reduction in dataset size while still producing high-fidelity images of the sample.
- Saugat Kandel
- , Tao Zhou
- & Mathew J. Cherukara
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Article
| Open AccessCompact all-fiber quantum-inspired LiDAR with over 100 dB noise rejection and single photon sensitivity
LiDARs exploiting quantum correlations provide enhancement in noise resilience and sensitivity, but high-power classical sources offer much higher operating distances. Here, the authors show how to exploit high power classical time-frequency correlations to keep the best of both worlds.
- Han Liu
- , Changhao Qin
- & Amr S. Helmy
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Article
| Open AccessOperando monitoring of thermal runaway in commercial lithium-ion cells via advanced lab-on-fiber technologies
Operando monitoring of thermal runaway in Li-ion batteries is critical. Here, authors develop an optical fiber sensor capable of insertion into 18650 batteries to monitor internal temperature and pressure during thermal runaway, facilitating battery safety assessment and early warning capability.
- Wenxin Mei
- , Zhi Liu
- & Tuan Guo
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Article
| Open AccessInfrared spectroscopic laser scanning confocal microscopy for whole-slide chemical imaging
Chemical imaging, including infrared spectroscopic microscopy with molecular sensitivity, is useful for label-free biomedical analyses, but is limited by slow speed and poor image quality. Here, the authors design a fast mid-infrared microscope with low noise and high spatial resolution for high-throughput imaging of whole slides.
- Kevin Yeh
- , Ishaan Sharma
- & Rohit Bhargava
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Article
| Open AccessSwitch of cell migration modes orchestrated by changes of three-dimensional lamellipodium structure and intracellular diffusion
How do cells regulate their migration speed and direction? Here, authors discover that keratocyte cells can reversibly switch between different migration modes, by changing the 3D lamellipodium shape and intracellular diffusion.
- Chao Jiang
- , Hong-Yu Luo
- & Hui Li
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Article
| Open AccessA universal metasurface antenna to manipulate all fundamental characteristics of electromagnetic waves
The authors show a universal metasurface antenna capable of simultaneously and independently controlling all five fundamental properties of electromagnetic waves, including amplitude, phase, frequency, polarization, and momentum.
- Geng-Bo Wu
- , Jun Yan Dai
- & Chi Hou Chan
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Article
| Open AccessHypothermal opto-thermophoretic tweezers
Traditional optical tweezers require high laser powers risking photothermal damage of the trapped objects. Here, the authors present hypothermal opto-thermophoretic tweezers (HOTTs), which use environmental cooling to simultaneously enhance thermophoretic trapping force at low laser powers and suppress the thermal damage to trapped objects.
- Pavana Siddhartha Kollipara
- , Xiuying Li
- & Yuebing Zheng
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Article
| Open AccessSuper-resolution multicolor fluorescence microscopy enabled by an apochromatic super-oscillatory lens with extended depth-of-focus
Conventional super-oscillatory devices suffer from numerical-aperture related issue including depth of focus, chromatic dispersion, and focusing, Here, the authors utilised multi-objective genetic algorithm to optimise the design and experimentally demonstrated lens with an extended depth of focus, ultra-large working distance and suppressed side-lobes.
- Wenli Li
- , Pei He
- & Yiting Yu
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Article
| Open AccessCarrier-envelope phase on-chip scanner and control of laser beams
Measurement and control of the carrier-envelope phase (CEP) is essential for applications of few-cycle laser beams. The authors present a compact on-chip, ambient-air, CEP scanning probe and show a 3D map of spatial changes of CEP and demonstrate CEP control in the focal volume with a spatial light modulator.
- Václav Hanus
- , Beatrix Fehér
- & Péter Dombi
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Article
| Open AccessExciton Superposition across Moiré States in a Semiconducting Moiré Superlattice
The moiré lattice of trilayer WSe2 and monolayer WS2 host interlayer excitons localized at different moiré sites. Using an electric field, the authors tune the superposition between two moiré sites via hybridization with intralayer excitons in WSe2.
- Zhen Lian
- , Dongxue Chen
- & Su-Fei Shi
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Article
| Open AccessHandheld snapshot multi-spectral camera at tens-of-megapixel resolution
Current multispectral video cameras can hardly scale up beyond megapixel resolution and do not apply to large-scale scenes. The authors design a tens-ofmegapixel handheld multi-spectral imaging scheme, build a setup achieving 65-megapixel videography of 12 wavebands, and show its wide applications.
- Weihang Zhang
- , Jinli Suo
- & Qionghai Dai
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Article
| Open AccessDual-comb optomechanical spectroscopy
Spectroscopic gas sensing with high sensitivity and selectivity finds an increasing number of applications. Here, the authors report an approach to ultrasensitive multiplexed gas sensing by integrating dual-comb spectroscopy with cavity optomechanics.
- Xinyi Ren
- , Jin Pan
- & Heping Zeng
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Article
| Open AccessMulticolor lifetime imaging and its application to HIV-1 uptake
Multicolor imaging employing genetically-encodable fluorescent proteins permits spatiotemporal live cell imaging of multiple cues. Here, authors use multicolor lifetime imaging to visualize quadruple-labelled human immunodeficiency viruses within cellular contexts.
- Tobias Starling
- , Irene Carlon-Andres
- & Sergi Padilla-Parra
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Article
| Open AccessEnabling low-drift flexible perovskite photodetectors by electrical modulation for wearable health monitoring and weak light imaging
Defects and ion migration in perovskites hinder their potential as active material for flexible photodetectors. Here, the authors provide an electrical field modulation strategy to enhance the operational stability and the signal-to-noise ratio of flexible perovskite photodetectors.
- Yingjie Tang
- , Peng Jin
- & Bowen Zhu
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Article
| Open AccessUltra-wideband optical coherence elastography from acoustic to ultrasonic frequencies
Understanding the mechanical properties of materials is critical in many fields, from soft hydrogels to biological tissues, yet current measurement methods lack the spatial and time resolution to characterize samples with complex structures. Here, the authors show non-invasive elastography technique offering advancements in resolution, sensitivity, and measurement frequencies.
- Xu Feng
- , Guo-Yang Li
- & Seok-Hyun Yun
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Article
| Open AccessEGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial
By using tumor-specific fluorescent tracers, fluorescence molecular imaging (FMI) can be used to visualize tumor tissues with high specificity. Here the authors report the results of a phase II trial to evaluate the diagnostic accuracy of an EGFR-targeted FMI for intraoperative margin assessment in patients with oral squamous cell carcinoma.
- Jaron G. de Wit
- , Jasper Vonk
- & Max J. H. Witjes
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Article
| Open AccessNon-interferometric stand-alone single-shot holographic camera using reciprocal diffractive imaging
An ideal holographic camera acquires depth information about an object by measuring the light field. Here, the authors present a reference-free single-shot holographic image sensor that freely focuses the image of real-world objects via reciprocal diffractive imaging.
- Jeonghun Oh
- , Herve Hugonnet
- & YongKeun Park
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Article
| Open AccessRevealing low-loss dielectric near-field modes of hexagonal boron nitride by photoemission electron microscopy
The application of time-resolved photoemission electron microscopy (TR-PEEM) to non-conducting materials is challenging. Here, the authors report the TR-PEEM characterization of near-field dielectric modes and photoemission properties of insulating hexagonal boron nitride structures on indium tin oxide/glass substrates.
- Yaolong Li
- , Pengzuo Jiang
- & Qihuang Gong
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Article
| Open AccessMachine learning assisted quantum super-resolution microscopy
Quantum super-resolution techniques take advantage of the non-classical nature of the quantum emitters, but are time-consuming. Here, the authors present a machine learning-assisted approach for fast antibunching-based super-resolution imaging, with a 12-fold speed up over the conventional approach
- Zhaxylyk A. Kudyshev
- , Demid Sychev
- & Vladimir M. Shalaev
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Article
| Open AccessOver-coupled resonator for broadband surface enhanced infrared absorption (SEIRA)
Nanoresonator is proven to be an excellent platform for molecular detection, yet a set of them is necessary to identify a molecule fingerprint. Here, the authors utilise low quality resonators with large radiative losses, despite its lower quality factor, to identify molecular absorption spectrum between 5 and 10 μm.
- Laura Paggi
- , Alice Fabas
- & Patrick Bouchon
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Article
| Open AccessAtmospheric turbulence strength distribution along a propagation path probed by longitudinally structured optical beams
Knowledge of atmospheric turbulence strength at various distances is critical for the development of effective solutions for turbulence mitigation. Here, authors demonstrate how to probe the distribution of turbulence strength along a propagation path with multiple longitudinally structured optical beams
- Huibin Zhou
- , Xinzhou Su
- & Alan E. Willner
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Article
| Open AccessQuadrupolar excitons and hybridized interlayer Mott insulator in a trilayer moiré superlattice
The authors observe the signatures of quadrupolar excitons in a WSe2-WS2-WSe2 trilayer moiré superlattice, originating from the hybridization of the WSe2 valence moiré flatbands. They further use electrostatic gating to reveal a hybridized interlayer Mott insulator state, with holes shared between the two WSe2 layers but laterally confined in moiré superlattices.
- Zhen Lian
- , Dongxue Chen
- & Su-Fei Shi
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Article
| Open AccessμeV electron spectromicroscopy using free-space light
The authors present μeV electron spectromicroscopy, a technique that combines free-space light and electron beams to achieve unmatched spatial and spectral resolution. This approach enables detailed investigation of photonic structures, promising advancements in microscopy and quantum optics.
- Yves Auad
- , Eduardo J. C. Dias
- & Mathieu Kociak
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Article
| Open AccessDeconvolution volumetric additive manufacturing
Volumetric additive manufacturing generally suffers from systematic undercuring of fine features, which limits its application range. Here, authors develop a model to predict print time variation with feature size and propose a deconvolution method, enabling precise fabrication of intricate structures.
- Antony Orth
- , Daniel Webber
- & Chantal Paquet
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Article
| Open AccessPhase intensity nanoscope (PINE) opens long-time investigation windows of living matter
The authors present phase intensity nanoscope (PINE), which uses an integrated phase-intensity multilayer thin film to localize randomly distributed nanoprobes and resolve sub-10 nm cellular architectures. They demonstrate dynamic imaging of nanoscopic reorganization over 250 h and find that nanoscale rearrangements emerging into macroscale rearrangements are synchronized.
- Guangjie Cui
- , Yunbo Liu
- & Somin Eunice Lee