Nutritional supplements articles from across Nature Portfolio

A metabolic product of excess niacin promotes vascular inflammation in preclinical models and is associated with increased rates of major adverse cardiovascular events in humans.

In the SSaSS trial, substituting regular table salt (100% sodium chloride) with an alternative containing 25% potassium chloride reduced the rate of stroke, major cardiovascular events and all-cause death.

A new study demonstrates a deficiency of NAD⁺ in patients with heart failure with preserved ejection fraction and indicates that restoration of NAD⁺ levels with nicotinamide supplementation might have therapeutic value to treat diastolic dysfunction in these patients.