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HOXA3 accelerates wound healing in diabetic and aged non-diabetic mammals
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High spontaneous integration rates of end-modified linear DNAs upon mammalian cell transfection
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Large scale screening of CRISPR guide RNAs using an optimized high throughput robotics system
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N1-methyl-pseudouridine is incorporated with higher fidelity than pseudouridine in synthetic RNAs
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AGO CLIP-based imputation of potent siRNA sequences targeting SARS-CoV-2 with antifibrotic miRNA-like activity
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Lentiviral and AAV-mediated expression of palivizumab offer protection against Respiratory Syncytial Virus infection
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Photocontrolled apoptosis induction using precursor miR-664a and an RNA carrier-conjugated with photosensitizer
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Stable duplex-linked antisense targeting miR-148a inhibits breast cancer cell proliferation
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Repurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase
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Non-specific interactions of antibody-oligonucleotide conjugates with living cells
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Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance
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Electroporation outperforms in vivo-jetPEI for intratumoral DNA-based reporter gene transfer
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Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes
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Viromers as carriers for mRNA-mediated expression of therapeutic molecules under inflammatory conditions
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Transcriptional repression of PTEN in neural cells using CRISPR/dCas9 epigenetic editing
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Induction of a local muscular dystrophy using electroporation in vivo: an easy tool for screening therapeutics
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Nanopore device-based fingerprinting of RNA oligos and microRNAs enhanced with an Osmium tag
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Messenger RNA translation enhancement by immune evasion proteins: a comparative study between EKB (vaccinia virus) and NS1 (influenza A virus)
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The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy
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Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts
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Generation of microalga Chlamydomonas reinhardtii expressing shrimp antiviral dsRNA without supplementation of antibiotics
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A T7 autogene-based hybrid mRNA/DNA system for long-term shRNA expression in cytoplasm without inefficient nuclear entry
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Physical-chemical measurement method development for self-assembled, core-shell nanoparticles
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Autophagy induction and PDGFR-β knockdown by siRNA-encapsulated nanoparticles reduce chlamydia trachomatis infection
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HPLC methods for purity evaluation of man-made single-stranded RNAs
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Artificial cationic oligosaccharides for heteroduplex oligonucleotide-type drugs
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Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
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Oral delivery of siRNA lipid nanoparticles: Fate in the GI tract
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The microRNA regulatory landscape of MSC-derived exosomes: a systems view
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Effective photo-enhancement of cellular activity of fluorophore-octaarginine antisense PNA conjugates correlates with singlet oxygen formation, endosomal escape and chromophore lipophilicity
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Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment
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Reconstruction of Toll-like receptor 9-mediated responses in HEK-Blue hTLR9 cells by transfection of human macrophage scavenger receptor 1 gene
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Library siRNA-generating RNA nanosponges for gene silencing by complementary rolling circle transcription
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White spot syndrome virus VP28 specific double-stranded RNA provides protection through a highly focused siRNA population
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Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment
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Human cellular CYBA UTR sequences increase mRNA translation without affecting the half-life of recombinant RNA transcripts
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Highly efficient transduction of primary adult CNS and PNS neurons
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Fluorescence-tunable Ag-DNA biosensor with tailored cytotoxicity for live-cell applications
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A RNA nanotechnology platform for a simultaneous two-in-one siRNA delivery and its application in synergistic RNAi therapy
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Ribonuclease H1-dependent hepatotoxicity caused by locked nucleic acid-modified gapmer antisense oligonucleotides
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Co-targeting EGFR and survivin with a bivalent aptamer-dual siRNA chimera effectively suppresses prostate cancer
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Synthetic long non-coding RNAs [SINEUPs] rescue defective gene expression in vivo
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Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer
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Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich’s ataxia
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The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates
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Combinatorial RNA Interference Therapy Prevents Selection of Pre-existing HBV Variants in Human Liver Chimeric Mice
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Efficient amplification of self-gelling polypod-like structured DNA by rolling circle amplification and enzymatic digestion
- Tomoya Yata
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Systemic Administration of siRNA via cRGD-containing Peptide
- Yuanyu Huang
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Comparison of non-canonical PAMs for CRISPR/Cas9-mediated DNA cleavage in human cells
- Yilan Zhang
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Shrimp injection with dsRNA targeting the microsporidian EHP polar tube protein reduces internal and external parasite amplification