Neutrophils

The formation of a provisional matrix is required for the onset of tissue repair. New research shows that neutrophils carry pre-existing matrix across organs into wounds, promoting fibroblast activation and scar formation.

The serotonin metabolite 5-HIAA is a potent ligand for GPR35 and promotes neutrophil recruitment to inflamed sites.

New research suggests entheseal neutrophils could have a role in the early phase of enthesitis in spondyloarthritis.

The transcription factor NFAT acts as a checkpoint in activated platelets to control their aggregation and interaction with neutrophils, keeping thrombotic and inflammatory responses in check.