Neurulation articles from across Nature Portfolio

Latest Research and Reviews

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  Coordination of alternative splicing and alternative polyadenylation revealed by targeted long read sequencing

  In this study using a targeted long read RNA sequencing approach called PL-Seq, the authors uncover coordination of alternative splicing and alternative polyadenylation within individual genes in Drosophila melanogaster.

  • Zhiping Zhang
  • Bongmin Bae
  • Pedro Miura

  ResearchOpen Access07 Sept 2023 Nature Communications

  Volume: 14, P: 5506
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  A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development

  The molecular mechanisms ensuring early face, brain, and skin formation are unclear. Here, the authors uncover a posttranslational pathway that controls cytoskeletal signaling circuits to coordinate ectodermal patterning and neurulation.

  • Anthony J. Asmar
  • Shaun R. Abrams
  • Achim Werner

  ResearchOpen Access26 Jul 2023 Nature Communications

  Volume: 14, P: 4499
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  Wnt4 and ephrinB2 instruct apical constriction via Dishevelled and non-canonical signaling

  Apical constriction is known to be critical for neural tube closure, but the signals that induce this process have not been fully characterized. Here Yoon et al. identify a signaling complex that instructs actomyosin contractions during apical constriction and show that it is required for neural tube closure.

  • Jaeho Yoon
  • Jian Sun
  • Ira O. Daar

  ResearchOpen Access20 Jan 2023 Nature Communications

  Volume: 14, P: 337
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  Time-lapse mechanical imaging of neural tube closure in live embryo using Brillouin microscopy

  • Chenchen Handler
  • Giuliano Scarcelli
  • Jitao Zhang

  ResearchOpen Access06 Jan 2023 Scientific Reports

  Volume: 13, P: 263
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  Live imaging and conditional disruption of native PCP activity using endogenously tagged zebrafish sfGFP-Vangl2

  Planar cell polarity (PCP) is critical for tissue-wide coordination and successful development. Here Jussila et al. generate a GFP-Vangl2 fusion for live imaging and discover a surprising directionality to the intercellular propagation of cell polarity, and ultimately link PCP defects with idiopathic scoliosis.

  • Maria Jussila
  • Curtis W. Boswell
  • Brian Ciruna

  ResearchOpen Access23 Sept 2022 Nature Communications

  Volume: 13, P: 5598
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  Embryo model completes gastrulation to neurulation and organogenesis

  Synthetic mouse embryos assembled from embryonic stem cells, trophoblast stem cells and induced extraembryonic endoderm stem cells closely recapitulate the development of wild-type and mutant natural mouse embryos up to embryonic day 8.5.

  • Gianluca Amadei
  • Charlotte E. Handford
  • Magdalena Zernicka-Goetz

  ResearchOpen Access25 Aug 2022 Nature

  Volume: 610, P: 143-153