Neural tube defects articles from across Nature Portfolio

Neural tube defects result from a failure in closing of the neural tube during gastrulation, which causes congenital malformations of the spinal cord and brain. Open neural tube defects result in exposure of the brain and/or spinal cord at birth and include anencephaly, encephaloceles, hydranencephaly, iniencephaly, schizencephaly and spina bifida.

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