Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Near-infrared spectroscopy is a form of non-invasive imaging that applies near-infrared radiation (wavelengths 780 nm to 3,000 nm) to chemicals or biological subjects to measure differential absorption. It can measure tissue oxygenation in blood including blood flow changes in the brain cortex for cognitive psychology research.
To achieve high-contrast in fluorescence imaging of deep tissues is challenging. Here, the authors develop NIR-II fluorescent small molecules with high brightness and emission extending to 1900 nm, enabling in vivo imaging of deep tissues with enhanced signal-to-background ratios.
Reducing the footprint of optical spectrometers is a critical requirement for many in-field applications. Now, a single black phosphorus photodetector with a wavelength-scale size enables mid-infrared computational spectrometry.
The biodistribution of the components of a messenger RNA vaccine following its administration in non-human primates can be non-invasively monitored by labelling the vaccine with a dual radionuclide–near-infrared probe.
