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| Open AccessDirect observation of a superconducting vortex diode
A nonreciprocal critical current is known as the superconducting diode effect (SDE). Here, the authors use SQUID-on-tip to study SDE in a EuS/Nb bilayer and find that the stray field from magnetized EuS creates screening currents in the Nb, which lead to SDE by affecting vortex flow dynamics.
- Alon Gutfreund
- , Hisakazu Matsuki
- & Yonathan Anahory
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Article
| Open AccessSingle test-based diagnosis of multiple cancer types using Exosome-SERS-AI for early stage cancers
Early detection of multiple cancers through a single method could be clinically important. Here the authors report the diagnostic performance for early detection for multiple cancers using surface-enhanced Raman spectroscopy (SERS) profiles of exosomes from a single blood test and artificial intelligence in a retrospective study design.
- Hyunku Shin
- , Byeong Hyeon Choi
- & Yeonho Choi
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Article
| Open AccessDiamagnetic mechanism of critical current non-reciprocity in multilayered superconductors
A superconducting diode effect was recently reported in Nb/V/Ta superlattices, but the mechanism is not yet clear. Here, the authors study non-reciprocal critical current in Al/InAs nanowires and propose a generic extrinsic mechanism involving field-generated diamagnetic currents, which may explain the earlier Nb/V/Ta results.
- Ananthesh Sundaresh
- , Jukka I. Väyrynen
- & Leonid P. Rokhinson
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Article
| Open AccessModular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field
Several strategies have been employed to enhance the tumor-targeting and anti-cancer properties of engineered bacteria. Here the authors describe the design of alternating magnetic field-manipulated bacteria engineered to release an anti-CD47 nanobody, promoting anti-tumor immune response in preclinical cancer models.
- Xiaotu Ma
- , Xiaolong Liang
- & Guangjun Nie
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Article
| Open AccessShape control in 2D molecular nanosheets by tuning anisotropic intermolecular interactions and assembly kinetics
Structuring organic films is of scientific and technological interest. Here, the authors use partially fluorinated organic molecules exhibiting strong intermolecular interactions to form extended 2D molecular nanosheets and control their shape through growth and desorption kinetics.
- Maximilian Dreher
- , Pierre Martin Dombrowski
- & Gregor Witte
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Article
| Open AccessDigital nanoreactors to control absolute stoichiometry and spatiotemporal behavior of DNA receptors within lipid bilayers
Resolving the stoichiometry of membrane protein interactions is challenging but is vital to understand cell signalling. Using lipid-bound DNA receptors as a model for membrane proteins, the authors present a platform to achieve stoichiometric, spatial and temporal control over their interactions.
- Vishal Maingi
- , Zhao Zhang
- & Paul W. K. Rothemund
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Article
| Open AccessA generalizable nanopore sensor for highly specific protein detection at single-molecule precision
Sensitive and accurate approaches for protein detection have many potential applications. Here the authors show how engineered protein nanopore sensors, consisting of a monobody fused to a single-polypeptide nanopore, can be used for highly specific detection of proteins in complex biofluids.
- Mohammad Ahmad
- , Jeung-Hoi Ha
- & Liviu Movileanu
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Article
| Open AccessStrong synergy between gold nanoparticles and cobalt porphyrin induces highly efficient photocatalytic hydrogen evolution
The reaction efficiency of reactants near plasmonic nanostructures can be enhanced under illumination. Here, the authors show that the activity of a Co porphyrin molecular catalyst bound to Au nanoparticles is enhanced by plasmonic effects, yielding a high photocatalytic hydrogen generation rate.
- Huixiang Sheng
- , Jin Wang
- & Gang Lu
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Article
| Open AccessEnhanced nonlinear optomechanics in a coupled-mode photonic crystal device
The authors demonstrate the enhancement of nonlinear optomechanical measurement of mechanical motion by using pairs of coupled optical and mechanical modes in a 1D photonic crystal. The design harnesses the anisotropic mechanical elasticity to create strong coupling between mechanical modes.
- Roel Burgwal
- & Ewold Verhagen
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Article
| Open AccessSignatures of hot carriers and hot phonons in the re-entrant metallic and semiconducting states of Moiré-gapped graphene
Significant attention has been devoted to understanding the low-electric-field properties of carriers in moiré graphene, but high-electric-field transport has not been as well explored. Here, the authors find non-monotonic transport behavior at moiré minigaps due to competition between inter-band tunneling and coupling to out-of-equilibrium phonons.
- Jubin Nathawat
- , Ishiaka Mansaray
- & Jonathan P. Bird
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Article
| Open AccessHeterogeneous intercalated metal-organic framework active materials for fast-charging non-aqueous Li-ion capacitors
Ideal anode materials for Li-ion capacitors must demonstrate safety and fast-charging properties. Here, the authors propose intercalated metal-organic frameworks for fast-charging Li-ion capacitors using a combined machine learning design and spray-dry synthesis.
- Nobuhiro Ogihara
- , Masaki Hasegawa
- & Naoyuki Nagasako
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Article
| Open AccessSignature of quantum interference effect in inter-layer Coulomb drag in graphene-based electronic double-layer systems
Previous demonstrations of quantum interference in solids have mainly been limited to intra-layer transport within single conductors. Zhu et al. report a new type of inter-layer quantum interference in graphene-based double-layer devices, due to interference between carrier diffusion paths across the constituent layers.
- Lijun Zhu
- , Xiaoqiang Liu
- & Changgan Zeng
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Article
| Open AccessObservation of electron orbital signatures of single atoms within metal-phthalocyanines using atomic force microscopy
Resolving the orbital structure of single atoms is challenging and of great importance for understanding basic chemistry. Here, the authors demonstrate that the orbital occupation difference of single Fe/Co atoms within molecules can be distinguished with high resolution AFM imaging and spectroscopy.
- Pengcheng Chen
- , Dingxin Fan
- & Nan Yao
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Article
| Open AccessMechano-boosting nanomedicine antitumour efficacy by blocking the reticuloendothelial system with stiff nanogels
Nanomedicine proofed to be efficient in cancer therapy but rapid clearance from blood circulation by reticuloendothelial system (RES) severely limits the antitumor efficacy. Here, the authors design a series of nanogels with distinctive stiffness and investigate how nanogel mechanical properties could be leveraged to overcome RES.
- Zheng Li
- , Yabo Zhu
- & Zifu Li
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Article
| Open AccessSustainable methane utilization technology via photocatalytic halogenation with alkali halides
A sustainable photocatalytic methane halogenation strategy is developed for methyl halide production using low-cost alkali halides over Cu-doped TiO2 nanostructures. Copper sites ultimately stabilize *CH3 to promote reaction with Cl− to form CH3Cl.
- Jun Ma
- , Can Zhu
- & Yujie Xiong
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Article
| Open AccessHybrid spin Hall nano-oscillators based on ferromagnetic metal/ferrimagnetic insulator heterostructures
Spin-hall nano-oscillators have potential for use in neuromorphic computing applications. Normally they are based around combination platinum and permalloy. Here, the authors combine a permalloy ferromagnet with a low magnetic damping ferrimagnet, leading to significantly improved performance.
- Haowen Ren
- , Xin Yu Zheng
- & Andrew D. Kent
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Article
| Open AccessAlphaFlow: autonomous discovery and optimization of multi-step chemistry using a self-driven fluidic lab guided by reinforcement learning
Autonomous exploration of materials design space is hindered by its high dimensionality and the scarcity of data. In this work, we present AlphaFlow, a self-driven lab guided by reinforcement learning that enables accelerated discovery and optimization of multi-step chemistries.
- Amanda A. Volk
- , Robert W. Epps
- & Milad Abolhasani
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Article
| Open AccessHybrid molecular graphene transistor as an operando and optoelectronic platform
Molecular electronics represents an avenue to enrich conventional electronics, but its reproducibility and scalability are still challenging. Here, the authors report the realization of multifunctional hybrid molecular graphene field effect transistors enabling operando spectroscopy and the implementation of optoelectronic logic gates.
- Jorge Trasobares
- , Juan Carlos Martín-Romano
- & Daniel Granados
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| Open AccessControlling doping efficiency in organic semiconductors by tuning short-range overscreening
Doping is widely adopted to make organic semiconductors more conductive, yet the impact of molecular electronic properties on doping performance is still not fully understood. Armleder et al. compute host-dopant interactions and show that a short-range overscreening effect strongly affects conductivity.
- Jonas Armleder
- , Tobias Neumann
- & Artem Fediai
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| Open AccessMammalian-brain-inspired neuromorphic motion-cognition nerve achieves cross-modal perceptual enhancement
Inspired by the multisensory cue integration in macaque’s brain for spatial perception, the authors develop a neuromorphic motion-cognition nerve that achieves cross-modal perceptual enhancement for robotics and wearable applications.
- Chengpeng Jiang
- , Jiaqi Liu
- & Wentao Xu
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Article
| Open AccessCreating complex protocells and prototissues using simple DNA building blocks
Building synthetic protocells and prototissues hinges on the formation of biomimetic skeletal frameworks. Here, the authors harness simplicity to create complexity by assembling DNA subunits into structural frameworks which support membrane-based protocells and prototissues.
- Nishkantha Arulkumaran
- , Mervyn Singer
- & Jonathan R. Burns
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| Open AccessLantern-shaped flexible RNA origami for Smad4 mRNA delivery and growth suppression of colorectal cancer
mRNA delivery has shown great potential in the treatment of various diseases. Here, the authors develop a lantern-shaped flexible origami for nanolization of single mRNA molecules and demonstrate efficient delivery of Smad4 mRNA, achieving suppression of colorectal cancer tumour growth.
- Muren Hu
- , Chang Feng
- & Xiaoli Zhu
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Article
| Open AccessNanoarchitecture factors of solid electrolyte interphase formation via 3D nano-rheology microscopy and surface force-distance spectroscopy
Characterization of the solid electrolyte interphase formed on Li-ion battery electrodes presents significant experimental challenges. Here the authors use atomic force microscopy-based force-spectroscopy techniques to depict the initial interphase formation in two different electrolyte classes.
- Yue Chen
- , Wenkai Wu
- & Oleg V. Kolosov
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Article
| Open AccessQuantum enhanced radio detection and ranging with solid spins
Quantum sensors based on NV centers in diamond are well established, however the sensitivity of detection of high-frequency radio signals has been limited. Here the authors use nanoscale field-focusing to enhance sensitivity and demonstrate ranging for GHz radio signals in an interferometer set-up.
- Xiang-Dong Chen
- , En-Hui Wang
- & Fang-Wen Sun
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Article
| Open AccessUltrafast motion in a third generation photomolecular motor
Controlling molecular motion at nanoscale is important for the design of nanomachines. Here the authors use ultrafast vibrational and electronic spectroscopy to characterize the mechanism of motion of a light driven molecular motor designed to support translational movement.
- Palas Roy
- , Wesley R. Browne
- & Stephen R. Meech
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Article
| Open AccessIridium oxide nanoribbons with metastable monoclinic phase for highly efficient electrocatalytic oxygen evolution
Well-defined metastable phase nanostructures are a core issue for catalyst design. Here, the authors report metastable monoclinic phase IrO2 nanoribbons obtained via a molten-alkali mechanochemical method, which exhibit intrinsic high performance towards the acidic oxygen evolution reaction.
- Fan Liao
- , Kui Yin
- & Qi Shao
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Article
| Open AccessMechanical metamaterials made of freestanding quasi-BCC nanolattices of gold and copper with ultra-high energy absorption capacity
The fabrication of freestanding 3D lattice structures with beam diameters less than 100 nm is a considerable challenge. Here, the authors report quasi-BCC nanolattices of gold and copper, featuring beam diameters as low as 34 nm, that demonstrate an exceptionally high capacity for energy absorption.
- Hongwei Cheng
- , Xiaoxia Zhu
- & Jinglai Duan
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Article
| Open AccessLifetime over 10000 hours for organic solar cells with Ir/IrOx electron-transporting layer
Long-term stability of organic solar cells is critical to promote practical applications. Here, the authors utilize iridium/iridium oxide nanoparticles as the electron-transporting material and realize enhanced device stabilities under thermal aging with T70 of over 10000 h.
- Yanxun Li
- , Bo Huang
- & Huiqiong Zhou
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Article
| Open AccessSite-specific anisotropic assembly of amorphous mesoporous subunits on crystalline metal–organic framework
Porous anisotropic nanohybrids have attracted attention because of their unique properties including high surface area, tunable pore structures and controllable compositions. Here, authors report a selective occupation strategy to achieve site-specific anisotropic growth of amorphous mesoporous subunits on crystalline MOFs.
- Minchao Liu
- , Cheng Shang
- & Xiaomin Li
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| Open AccessResearch on scalable graphene faces a reproducibility gap
More than a decade after the first demonstration of large-scale graphene synthesis by chemical vapor deposition, the commercialization of graphene products is limited not only by price, but also by consistency, reproducibility, and predictability. Here, the author discusses the reproducibility issues in the field and proposes possible solutions to improve the reliability of published results.
- Peter Bøggild
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Article
| Open AccessMetasurface-stabilized optical microcavities
Microcavities concentrate light in tiny volumes and are important, e.g., for semiconductor lasers and nonlinear optics. In this paper, metasurfaces are introduced to realize microcavities with arbitrary mode profiles.
- Marcus Ossiander
- , Maryna Leonidivna Meretska
- & Federico Capasso
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Article
| Open AccessHighly-twisted states of light from a high quality factor photonic crystal ring
Twisted light in the form of orbital angular momentum (OAM) can provide an additional spatial dimension for information transmission. Here, the authors demonstrate a prescription for OAM generation using photonic crystal ring resonators, in which high cavity quality factors (up to 106) are retained.
- Xiyuan Lu
- , Mingkang Wang
- & Kartik Srinivasan
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Article
| Open AccessBright Tm3+-based downshifting luminescence nanoprobe operating around 1800 nm for NIR-IIb and c bioimaging
Fluorescence imaging in the near-infrared region yields high-quality images that overcome the current depth limitations. Here, the authors report a Tm3 + -based nanoprobe for NIR-IIb/c imaging, providing references to future bioimaging beyond 1700 nm.
- Yulei Chang
- , Haoren Chen
- & Xianggui Kong
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Article
| Open AccessVariant Plateau’s law in atomically thin transition metal dichalcogenide dome networks
Plateau’s law describes the configuration (joint angles ~120°) of soap bubbles, foams and cellular structures, but its applicability to solid films has not been explored. Here, the authors report the observation of a variant Plateau’s law in networks of nanobubbles made of 2D semiconductors, measuring largely varying joint angles due to the thickness-dependent effective surface tension.
- Boqing Liu
- , Tanju Yildirim
- & Yuerui Lu
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Article
| Open AccessWafer-scale and universal van der Waals metal semiconductor contact
Laminated van der Waals (vdW) metallic electrodes can improve the contact of 2D electronic devices, but their scalability is usually limited by the transfer process. Here, the authors report a strategy to deposit vdW contacts onto various 2D and 3D semiconductors at the wafer scale.
- Lingan Kong
- , Ruixia Wu
- & Yuan Liu
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Article
| Open AccessSnake venom-defined fibrin architecture dictates fibroblast survival and differentiation
A new snake venom-controlled defined fibrin system with stable, reproducible, and independently tuned biophysical properties is established. Employing the system, the authors find fibrin architecture can precisely control fibroblast differentiation.
- Zhao Wang
- , Jan Lauko
- & Alan E. Rowan
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Article
| Open AccessDeformation constraints of graphene oxide nanochannels under reverse osmosis
Nanochannels in laminated graphene oxide nanosheets featuring confined mass transport have attracted interest in multiple research fields. As an important aspect for efficient pressure-driven membrane processes, authors investigate the response and deformation behaviours of such nanochannels to different external conditions.
- Kecheng Guan
- , Yanan Guo
- & Hideto Matsuyama
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Article
| Open AccessGene-encoding DNA origami for mammalian cell expression
DNA origami may enable more versatile gene delivery applications through its ability to create custom nanoscale objects. Here the authors show that genes folded in DNA origami with custom scaffolds express efficiently when delivered to mammalian cells and can be assembled into multimeric arrays to deliver and express defined ratios of multiple genes simultaneously.
- Jessica A. Kretzmann
- , Anna Liedl
- & Hendrik Dietz
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Article
| Open AccessTwisted bilayer zigzag-graphene nanoribbon junctions with tunable edge states
Twisted 2D materials have recently emerged as a controllable quantum simulator platform. Here, the authors apply the same approach to tune the edge states of zigzag graphene nanoribbons, showing a unique degree of freedom represented by the lateral stacking offset of the 1D nanostructures.
- Dongfei Wang
- , De-Liang Bao
- & Hong-Jun Gao
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Article
| Open AccessA general thermodynamics-triggered competitive growth model to guide the synthesis of two-dimensional nonlayered materials
2D nonlayered materials exhibit interesting properties for catalysis, nanoelectronics and spintronics applications, but their growth is still challenging. Here, the authors report a theoretical model and an experimental strategy to synthesize various 2D nonlayered transition metal oxides with room-temperature magnetic properties.
- Zijing Zhao
- , Zhi Fang
- & Yanglong Hou
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Article
| Open AccessSub-resolution contrast in neutral helium microscopy through facet scattering for quantitative imaging of nanoscale topographies on macroscopic surfaces
Neutral helium microscopy is a completely nondestructive, surface-sensitive imaging technique. Here, the authors demonstrate sub-resolution contrast using an advanced facet scattering model to reconstruct the topography of technological thin films in the ångström range.
- Sabrina D. Eder
- , Adam Fahy
- & Paul C. Dastoor
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Article
| Open AccessGeneral duality and magnet-free passive phononic Chern insulators
Understanding and controlling symmetry in nature is of paramount importance. In this work, the authors reveal an unexpected effect of the general duality relation between piezoelectricity and piezomagnetism on their symmetries, enabling novel phononic Chern insulators.
- Qicheng Zhang
- , Li He
- & A. T. Charlie Johnson
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Article
| Open AccessMicrowave-assisted design of nanoporous graphene membrane for ultrafast and switchable organic solvent nanofiltration
Layered 2D materials can be used for organic solvent nanofiltration (OSN) membrane fabrication due to precise molecular sieving by the interlayer structure and stability in harsh conditions. Here authors synthesise sp2-enriched nanoporous graphene by microwave treatment and demonstrate its excellent OSN performance.
- Junhyeok Kang
- , Yeongnam Ko
- & Dae Woo Kim
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Article
| Open AccessFrom nanohole to ultralong straight nanochannel fabrication in graphene oxide with swift heavy ions
While porous graphene oxide with nm-sized pores can be of great interest to biofluidic and energy storage applications, achieving precisely controlled porosity remains a technical challenge. Here, the authors exploit swift heavy ions to create uniform nanoholes and ultralong straight nanochannels in GO films.
- Andrzej Olejniczak
- & Ruslan A. Rymzhanov
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Article
| Open AccessLong-lived electronic spin qubits in single-walled carbon nanotubes
Spins defined in single-walled carbon nanotubes promise ultra-long spin relaxation times, but qubit implementations require confinement of isolated spins. Here the authors report highly confined long-lived electron spins in chemically functionalized nanotubes and demonstrate their coherent control.
- Jia-Shiang Chen
- , Kasidet Jing Trerayapiwat
- & Xuedan Ma
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Article
| Open AccessNanoscale three-dimensional fabrication based on mechanically guided assembly
3D fabrication via mechanically guided assembly has greatly progressed in the recent years, but has not been applicable for nanodevices. Here the authors suggest a configuration-designable 3D nanofabrication through a nanotransfer printing and design of the substrate’s mechanical characteristics.
- Junseong Ahn
- , Ji-Hwan Ha
- & Inkyu Park
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Article
| Open AccessUltra-wideband-responsive photon conversion through co-sensitization in lanthanide nanocrystals
The authors report a multi-ion co-sensitization strategy to achieve ultra-wideband-responsive photon conversion of lanthanide nanocrystals from UV to NIR. They demonstrate applications for white light-based bioimaging and information encryption.
- Zhao Jiang
- , Liangrui He
- & Wanwan Li
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Article
| Open AccessControlled sequential in situ self-assembly and disassembly of a fluorogenic cisplatin prodrug for cancer theranostics
Manipulating molecular self-assembly and disassembly in vivo may permit temporal control of drug delivery and release. Here, the authors report a fluorogenic cisplatin prodrug for cancer theranostics by leveraging stimuli-triggered in situ self-assembly and intracellular disassembly processes.
- Xidan Wen
- , Rui Zhang
- & Deju Ye
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Article
| Open AccessEmergence of chaos in a compartmentalized catalytic reaction nanosystem
In situ studies of the spatio-temporal behavior of individual well-defined nanosized compartments are paramount in heterogeneous catalysis. Here, a transition from oscillating to chaotic behaviour was observed in catalytic hydrogen oxidation on a rhodium nanocrystal serving as a model of a single catalytic particle.
- Maximilian Raab
- , Johannes Zeininger
- & Günther Rupprechter