Mutation articles from across Nature Portfolio

Reporting in Science, a team from Google DeepMind describe AlphaMissense, a tool to predict the pathogenicity of missense variants.

A method to identify and analyze clonal hematopoiesis in clinical blood samples at single-cell resolution reveals cell-intrinsic and paracrine effects of DNMT3A mutations in circulating monocytes, T cells and natural killer cells in the setting of heart failure.