Motor control

Motor control refers to the process by which the nervous system coordinates the muscle and limbs to achieve a desired movement or set of actions. This includes the ability to anticipate, adjust and respond to deviations from the desired action.

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  • News and Views |

    Chiot and colleagues investigated whether peripheral macrophages play a role in amyotrophic lateral sclerosis (ALS) pathology, finding that macrophages along peripheral motor neuron axons react to neurodegeneration. Modifying reactive oxygen species (ROS) signaling in peripheral macrophages, using bone marrow cell replacement, reduces both macrophage and microglia inflammatory response, delays pathology and increases survival in ALS mouse models.

    • P. Hande Özdinler
  • News and Views |

    In the presence of recording instabilities, the performance of brain–computer interfaces can be robustly maintained by exploiting ‘hidden’ structures underlying neural activity.

    • Lahiru N. Wimalasena
    • , Lee E. Miller
    •  & Chethan Pandarinath
  • News and Views |

    A new study shows that mapping neural signals directly to word sequences produces lower error rates in speech decoding than previous methods that use motor or auditory based features. This suggests that using higher-level language goals can aid decoding algorithms for neural speech prostheses.

    • Gregory B. Cogan
    Nature Neuroscience 23, 471-472
  • News and Views |

    Motor learning is composed of explicit ‘strategic’ components and implicit ‘automatic’ components. Miyamoto and colleagues reveal how these components work together during visuomotor adaptation, providing evidence that an implicit component corrects for a noisy explicit process.

    • Olivier Codol
    • , Giacomo Ariani
    •  & Jonathan A. Michaels
    Nature Neuroscience 23, 298-300
  • Research Highlights |

    In mice, temporally patterned inputs to the motor cortex that controls the forelimb are required for a well-trained reaching behaviour.

    • Natasha Bray