Monokines articles from across Nature Portfolio

Monokines are cytokines produced mainly by monocytes and macrophages for function in the immune system. Monokines can function as chemoattractants for guiding neutrophil migration.

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15 November 2017 | Open Access

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis

Spondyloarthritis is an inflammatory disease with Th17 cells implicated in the pathogenesis. Here the authors show that patients with spondyloarthritis have increased numbers of GM-CSF-secreting blood and synovial lymphocytes, Th17 or not, that carry a unique transcriptional profile including enhanced GPR65 expression.
- M. H. Al-Mossawi
- , L. Chen
- & P. Bowness
Nature Communications 8, 1510

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Monokines articles from across Nature Portfolio

Latest Research and Reviews

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis

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