Molecular biophysics

Molecular biophysics is the study of the physical principles governing biomolecular systems. It seeks to explain biological function in terms of molecular structure, dynamics and organization, from single molecules to supramolecular structures.

Latest Research and Reviews

News and Comment

  • Research Highlights |

    Li, W., Hu, J., Shi, B. et al. showed that the appropriate phase separation property of the protein AKAP95 was required for its regulation of splicing and expression of cancer-related genes, thereby contributing to tumorigenesis.

    • Ulrike Harjes
  • Comments and Opinion
    | Open Access

    Chemical reaction networks (CRNs) are prototypical complex systems because reactions are nonlinear and connected in intricate ways, and they are also essential to understand living systems. Here, the author discusses how recent developments in nonequilibrium thermodynamics provide new insight on how CRNs process energy and perform sophisticated tasks, and describes open challenges in the field.

    • Massimiliano Esposito
  • News and Views |

    Is a nanoscale hydrophobic bowl wet or dry when dissolved in water? It turns out that the answer depends on the architecture of its rim. A molecular host decorated with four methyl groups around its rim pointing inward, rather than up, has now been shown to expel water from the bowl, making it dry and sticky.

    • Shekhar Garde
    Nature Chemistry 12, 587-588