Microbiota

The microbiota is a collective term for the micro-organisms that live in or on the human body. Specific clusters of microbiota are found on the skin or in the gastrointestinal tract, mouth, vagina and eyes.

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  • News and Views |

    Changes in the gut microbiome are thought to be important environmental triggers for inflammatory forms of arthritis, including rheumatoid arthritis. Could interactions between gut parasites, such as helminths, and gut microbiota be the key to normalizing an unbalanced microbiome and preventing arthritis?

    • Gillian Coakley
    •  & Nicola L. Harris
  • Comments and Opinion |

    In this Viewpoint article, we asked four scientists working on the cancer microbiome to provide their opinions on the current state of the field, where the research is heading and the challenges of implementing this field for clinical utility.

    • Eran Elinav
    • , Wendy S. Garrett
    • , Giorgio Trinchieri
    •  & Jennifer Wargo
  • Comments and Opinion |

    To deliver precision therapeutics, microbiome-based medicine will require precision of language, logic and numerical accuracy. Epidemiological lessons of the past suggest that attempts to link almost everything in modern life with the microbiome as a risk factor for disease, without rapprochement with plausible mechanisms, will generate controversy rather than consensus.

    • Fergus Shanahan
    •  & Colin Hill
  • Comments and Opinion |

    A crucial consideration for the clinical application of any burgeoning science is when the understanding of that field can be implemented without the risk of unforeseen harm. In our opinion, the need for caution is particularly urgent with respect to increasingly prevalent applications of microbiome science to medicine.

    • Kjersti Aagaard
    •  & Elizabeth Hohmann
    Nature Medicine 25, 874-876