Microbial genetics

Microbial genetics is the study of the mechanisms of heritable information in microorganisms, including bacteria, archaea, viruses and some protozoa and fungi.

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Latest Research and Reviews

News and Comment

  • News & Views |

    Advances in CRISPR–Cas tools coupled with innovative screening and bioinformatic pipelines make it possible to conduct strain-specific and site-specific genome editing within a microbial community without the need for prior culturing or engineering.

    • Connie W. Y. Ha
    •  & Suzanne Devkota
  • Research Highlights |

    A study in Nature Communications shows that horizontal transfer of bacterial chromosomes by phage-mediated lateral transduction renders them more mobile than many classically defined mobile genetic elements, including plasmids and transposons.

    • Dorothy Clyde
  • Comments & Opinion
    | Open Access

    An outcome of phage infection, lateral transduction, has been shown to mobilize chromosomal genes between bacterial cells at rates that exceed those of mobile genetic elements such as plasmids. Does this mean that the bacterial chromosome should be considered a mobile genetic element?

    • James P. J. Hall
  • Research Highlights |

    Researchers identified a single-effector Cas, Cas7-11, that architecturally diverges from previous CRISPR single- or multi-component systems and can possess RNA knockdown activity without detectable collateral activity in mammalian cells.

    • Lei Tang
    Nature Methods 18, 1276