Microbial genetics articles from across Nature Portfolio

This Genome Watch highlights recent metagenomics studies in fish that reveal unique microbiomes with low functional diversity, which could help to improve our understanding of host–microorganism dynamics in non-mammalian species.

High-resolution meta-omics have enabled the discovery of the microbial enzymes that inactivate an ulcerative colitis drug and predict subsequent treatment failure, an approach that could enable more personalized treatment of inflammatory bowel disease.

Julio Collado-Vides recalls two 2005 publications that provide a conceptual framework based on a statistical thermodynamics approach to quantitatively model the regulatory activity at promoters subject to regulation by multiple transcription factors.

CRISPR systems can be leveraged to direct recombinases to integrate gene-sized DNA sequences.

This Genome Watch article explores how portable sequencing technology is re-shaping the field of genomic epidemiology.

Genomics analyses of the Streptococcus pneumoniae pangenome show that gene essentiality depends on genetic context and can evolve over time.