Mesenchymal migration - Latest research and news

Latest Research and Reviews

Focal adhesions contain three specialized actin nanoscale layers

Focal adhesions are dynamic structures that link the cell to the extracellular matrix. Here, the authors report that focal adhesions contain tropomyosin-decorated actin filaments, and show evidence that suggests specific functions in adhesion dynamics and cell migration.
- Reena Kumari
- Katharina Ven
- Pekka Lappalainen
ResearchOpen Access21 Mar 2024 Nature Communications
Volume: 15, P: 2547
Assessing the fate and contribution of Foxd1-expressing embryonic precursors and their progeny in palatal development, homeostasis and excisional repair
- Georgia Nikoloudaki
- Douglas W. Hamilton
ResearchOpen Access29 Feb 2024 Scientific Reports
Volume: 14, P: 4969
Durotaxis and negative durotaxis: where should cells go?

This mini review highlights and compares the principles of durotaxis and negative durotaxis as part of cell migratory processes.
- Congcong Ji
- Yuxing Huang
ReviewsOpen Access16 Nov 2023 Communications Biology
Volume: 6, P: 1169
PPP2R1A regulates migration persistence through the NHSL1-containing WAVE Shell Complex

The WAVE regulatory complex activates Arp2/3 at the cell cortex and in membrane protrusions to generate persistent cell migration. Here authors show that PPP2R1A, a scaffold subunit of protein phosphatase 2, associates with an alternative form of the WAVE complex where WAVE, the subunit that activates Arp2/3, is replaced by NHSL1.
- Yanan Wang
- Giovanni Chiappetta
- Alexis M. Gautreau
ResearchOpen Access15 Jun 2023 Nature Communications
Volume: 14, P: 3541
Novel in vivo endometriotic models associated eutopic endometrium by implanting menstrual blood-derived stromal cells from patients with endometriosis
- Yuejian Zhang
- Tiantian He
- Xiaona Ma
ResearchOpen Access23 May 2023 Scientific Reports
Volume: 13, P: 8347
3D collagen migration patterns reveal a SMAD3-dependent and TGF-β1-independent mechanism of recruitment for tumour-associated fibroblasts in lung adenocarcinoma
- Yago Juste-Lanas
- Natalia Díaz-Valdivia
- Jordi Alcaraz
ResearchOpen Access26 Dec 2022 British Journal of Cancer
Volume: 128, P: 967-981