Melatonin articles from across Nature Portfolio

Melatonin is an endocrine hormone with a monoamine alkaloid structure, produced from the amino acid tryptophan. Melatonin is generated by the pineal gland in mammals. Melatonin is involved in entrainment of plant and animal circadian clocks via its action on melatonin receptors, expressed abundantly in the central nervous system, and through its direct antioxidant activity.

Latest Research and Reviews

Melatonin in type 2 diabetes mellitus and obesity

Type 2 diabetes mellitus and obesity are major public health challenges; emerging evidence suggests that melatonin is involved in the development of these disorders, opening new avenues for research. This Review discusses the effect of melatonin and its receptors on glucose homeostasis, obesity and type 2 diabetes mellitus.
- Angeliki Karamitri
- Ralf Jockers
Reviews07 Dec 2018 Nature Reviews Endocrinology
Volume: 15, P: 105-125
Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats
- G Özdemir
- Y Ergün
- E Ganiyusufoğlu
Research13 Jun 2014 Eye
Volume: 28, P: 1020-1027
Nocturnal urinary melatonin excretion is associated with non-dipper pattern in elderly hypertensives
- Kenji Obayashi
- Keigo Saeki
- Norio Kurumatani
Research11 Apr 2013 Hypertension Research
Volume: 36, P: 736-740
Melatonin Promotes Myelination by Decreasing White Matter Inflammation After Neonatal Stroke
- Sonia Villapol
- Sébastien Fau
- Olivier Baud
Research01 Jan 2011 Pediatric Research
Volume: 69, P: 51-55