Featured
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Perspective |
The sexual impact of androgenic anabolic steroid abuse an understudied phenomena
- Kole P. Akula
- , Lucien R. McBeth
- & Matthias D. Hofer
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Comment |
Response to the Commentary on: Safety and feasibility of percutaneous needle tunneling with platelet-rich plasma injections for Peyronie’s disease in the outpatient setting: a pilot study
- Ahmed S. Zugail
- , Muaath Alshuaibi
- & Sébastien Beley
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Article
| Open AccessAccurate diagnosis and effective treatment of abnormal meridians in erectile dysfunction patients based on infrared thermography: an electrophysiological technique study
- Zihao Wang
- , Kaifeng Liu
- & Pengjie Lu
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Correspondence |
Ghattas modification of inflatable penile prosthesis: a proposed surgical technique for efficient penile prosthesis implantation
- Osama Ghattas
- & Moustafa Gaber Menshawy
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Article |
The role and needs of family doctors in sexual medicine: contributions of a preliminary Portuguese qualitative study for a global action
- Margarida G. Rodrigues
- , Andreia A. Manão
- & Patrícia M. Pascoal
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Article |
Ursodeoxycholic acid ameliorates erectile dysfunction and corporal fibrosis in diabetic rats by inhibiting the TGF-β1/Smad2 pathway
- Irem Cavusoglu Nalbantoglu
- , Serhat Sevgi
- & Nuri Ihsan Kalyoncu
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Article
| Open AccessEvaluating the management trends for priapism and assessing the risk of priapism after in-office intracavernosal injections: a cross-sectional analysis
- Joon Yau Leong
- , Zachary J. Prebay
- & Paul H. Chung
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Perspective |
Adipose-derived stem cells: an upcoming novel therapeutic in the management of Erectile dysfunction post radical prostatectomy in prostate cancer patients
- Gargi Digholkar
- , Ryan Varghese
- & Rohit Sharma
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Perspective |
A phase 2 randomized, placebo-controlled crossover trial to evaluate safety and efficacy of platelet-rich plasma injections for Peyronie’s disease: clinical trial update
- Braian R. Ledesma
- , David A. Velasquez
- & Ranjith Ramasamy
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Review Article
| Open AccessA brief unstructured literature review on the history of paraphilias
- Safiye Tozdan
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Comment |
Response to the Commentary on: Intracavernosal pressure of the erect penis in children with hypospadias
- Michael Frumer
- & David Ben-Meir
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Article
| Open AccessEffect of bulbospongiosus muscle injection with botulinum-A toxin for treatment of lifelong premature ejaculation; a randomized controlled trial
- Khaled Almekaty
- , Ahmed Ghaith
- & Mohamed H. Zahran
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Correspondence
| Open AccessEfficacy of top flat magnetic stimulation for chronic pelvic pain in men: preliminary results
- Nicola Mondaini
- , Mauro Gacci
- & Rocco Damiano
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Article
| Open AccessPhosphodiesterase type 5 inhibitors do not prevent curvature progression but shorten pain duration in the active phase of Peyronie’s Disease: A retrospective cohort study
- Emil Durukan
- , Rune Kraglund
- & Mikkel Fode
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Correspondence |
Evaluating treatment pathways for Peyronie’s disease utilizing the TriNetX research registry
Peyronie’s disease (PD) is a fibrosing condition that affects the penis which leads to pain, curvature, sexual dysfunction, and psychological bother. Our retrospective cohort analysis aims to evaluate the current treatment pathways utilized for PD. We queried the TriNetX database for all adult men (≥18 years) with PD using the International Classification of Diseases-10 (ICD-10) code, N48.6, from the years 2003–2023. All interventions associated were assessed using Current Procedural Terminology (CPT) and Medical Prescription Normalized (RxNorm) codes. These included injection therapy, penile plication, plaque excision ± grafting, penile implant, and oral pentoxifylline. Of the 51011 PD cases identified, observation was the most common management (72.1%, n = 36 787). Pentoxifylline (70.0%, n = 4 699) was the most used single medical treatment followed by injection therapy (30.0%, n = 2 012). Penile plication was the most performed surgery for PD (55.1%, n = 1 793). Among patients who underwent multiple therapies (30.0%, n = 4 261), a progression of medical to surgical treatment only occurred in 24.5% (n = 1 044). PD is predominantly managed with observative measures, followed by medical therapy, and surgery. Surgical therapy occurred less frequently after medical treatment suggesting that few patients are interested in or may have limited access to a stepwise approach for the treatment of PD.
- Anushka Ghosh
- , Joon Yau Leong
- & Paul H. Chung
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Comment |
Commentary on “Phosphodiesterase type 5 inhibitors do not prevent curvature progression but shorten pain duration in the active phase of Peyronie’s disease: a retrospective cohort study”
- Celeste Manfredi
- , Eugenio Bologna
- & Leslie Claire Licari
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Article
| Open AccessRare, but potentially risky, high individual increase of self-reported sexual arousal in men, who have committed sexual offenses against children, while being confronted with experimental sexual stimuli — a retrospective data analysis
- Kirsten Jordan
- , Peter Fromberger
- & Jürgen Leo Müller
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Article |
Quality of information in Youtube videos on disorder of sexual development
- Serdar Toksoz
- & Mehmet Vehbi Kayra
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Article
| Open AccessPerioperative outcomes of penile prosthesis implantation in Germany: results from the GRAND study
- Nikolaos Pyrgidis
- , Gerald B. Schulz
- & Julian Marcon
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Article |
Intracavernosal pressure of the erect penis in children with hypospadias
- David Ben-Meir
- , Firas Abu Sbaih
- & Michael Frumer
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Article
| Open AccessPatients’ perspectives on informational needs surrounding gender-affirming vaginoplasty
- Alexandra Millman
- , Armin Gabela
- & Ervin Kocjancic
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Article |
A survey of exposure to the use of Xiaflex for the treatment of Peyronie’s disease among United States urology residency programs
- Justin Loloi
- , Kyle Schuppe
- & Ranjith Ramasamy
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Comment |
Commentary on: “Oxycodone prescription after inflatable penile prosthesis has risks of persistent use: a TriNetX Analysis”
- Corey Able
- , Pranjal Agrawal
- & Taylor P. Kohn
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Review Article |
The post-finasteride syndrome: possible etiological mechanisms and symptoms
- Herman H. J. Leliefeld
- , Frans M. J. Debruyne
- & Yakov Reisman
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Comment |
Commentary on: Low frequency neuromuscular electrical stimulation applied to the bulbospongiosus muscle
- Ilan Gruenwald
- , Arik Shechter
- & Alexander Greenstein
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Perspective |
Exploring representation of underrepresented minority men in a restorative therapy clinical trial for erectile dysfunction: addressing barriers and promoting inclusion
- Braian R. Ledesma
- , Jamie Thomas
- & Ranjith Ramasamy
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Perspective |
A response to recent penile enlargement industry media report
- Robert Valenzuela
- , Laurence Levine
- & Steven K. Wilson
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Review Article |
Hyperprolactinemia and male sexual function: focus on erectile dysfunction and sexual desire
- G. Corona
- , G. Rastrelli
- & M. Maggi
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Article |
A fragility index analysis of clinical trials evaluating low-intensity extracorporeal shockwave therapy for erectile dysfunction
- Joshua White
- , Francis Petrella
- & Ranjith Ramasamy
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Perspective |
The 100 most-cited publications on Peyronie’s disease: a bibliometric analysis and visualization study
- Dawei Gao
- , Yifeng Shen
- & Degui Chang
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Article |
Neoclitoral location may affect sexual function in transgender women: a preliminary pelvic MRI study
- Francesca Vedovo
- , Nicola Pavan
- & Carlo Trombetta
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Article
| Open AccessValue of prolonged scrotal drainage after penile prosthesis implantation: a multicenter prospective nonrandomized pilot study
- D. Osmonov
- , A. M. Ragheb
- & S. K. Wilson
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Comment |
Comment on “Complications and outcomes following injection of foreign material into the male external genitalia for augmentation: a single centre experience and systematic review”
- Javier Romero-Otero
- & Celeste Manfredi
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Perspective |
Penile implants have had a prominent place in the management of erectile dysfunction for the past 50 years
- John J. Mulcahy
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Comment
| Open AccessResponse to Comment on “Health outcomes and female genital mutilation/cutting: how much is due to the cutting itself?”
- Sophia D. Koukoui
- , Georgia J. Michlig
- & Crista E. Johnson-Agbakwu
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Article
| Open AccessWhat do women with sexual interest in children tell us about the assumed cause of their sexual interest in children, (non-)disclosure, and professional help?—Results of a qualitative content analysis
- Safiye Tozdan
- , Greta Hübener
- & Johanna Schröder
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Perspective |
The skills and experiences needed to enhance fellowship training in reproductive urology
- Akhil Muthigi
- , Joshua White
- & Ranjith Ramasamy
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Article |
Low frequency neuromuscular electrical stimulation applied to the bulbospongiosus muscle prolongs the ejaculation latency in a rat model
- Sezer Cizmeci
- , Sakir Ongun
- & Nergiz Durmus
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Article |
In vitro effect of relaxin in the rat corpus cavernosum under hyperglycemic and normoglycemic conditions
- Selin Acar-Sahan
- , Ozge Guner
- & Nergiz Durmus
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Comment |
Response to the Commentary on: Do pornography use and masturbation play a role in erectile dysfunction and relationship satisfaction in men?
- David L. Rowland
- & Krisztina Hevesi
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Editorial |
Child genital cutting and surgery across cultures, sex, and gender. Part 1: female, male, intersex—and trans? The difficulty of drawing distinctions
- Brian D. Earp
- , Jasmine Abdulcadir
- & Lih-Mei Liao
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Comment |
Do pornography use and masturbation play a role in erectile dysfunction and relationship satisfaction in men?
- Gunter De Win
- , Tim Jacobs
- & Sam Geuens
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Review Article |
The effect of penis size on partner sexual satisfaction: a literature review
- Shirley Loos
- , Peter De Wil
- & Sam Ward
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Article |
New findings regarding the influence of assistants on surgical outcomes in penile prosthesis implantation
- Shuo-chieh Wu
- , Amanda R. Swanton
- & Martin S. Gross
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Article
| Open AccessSexual activities and experiences in women who underwent genital cosmetic surgery: a cross-sectional study using data from the German Health and Sexuality Survey (GeSiD)
- Thula U. Koops
- , Christian Wiessner
- & Peer Briken
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Article |
Restorative therapy clinical trials for erectile dysfunction: a scoping review of endpoint measures
- Russell G. Saltzman
- , Roei Golan
- & Ranjith Ramasamy