Lipid peroxides
Lipid peroxides are oxidative degradation products of lipids, generated by a free radical chain reaction. Because of their abundance of reactive hydrogens, polyunsaturated fatty acids are highly susceptible to lipid peroxidation, which compromises the integrity and function of the cell membrane in which they reside.
Latest Research and Reviews
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Research
| Open Access
Targeting cPLA2 derived lipid hydroperoxides as a potential intervention for sarcopenia
Scientific Reports 10, 13968 -
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Research |
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
Nature 575, 688-692 -
Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis
A combination of electrochemistry and mass spectrometry to monitor the interaction of reactive species with supported lipid bilayers
Targeting cPLA2 derived lipid hydroperoxides as a potential intervention for sarcopenia
Sensitive determination of malondialdehyde in rat prostate by high performance liquid chromatography with fluorescence detection
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
Regioisomer-independent quantification of fatty acid oxidation products by HPLC-ESI-MS/MS analysis of sodium adducts