Ligand-gated ion channels : nature.com subject feedshttps://www.nature.com/subjects/ligand-gated-ion-channels.atom2024-03-29T11:19:48+00:00A release of local subunit conformational heterogeneity underlies gating in a muscle nicotinic acetylcholine receptorhttps://www.nature.com/articles/s41467-024-46028-x2024-02-27T00:00:00+00:002024-02-27T00:00:00+00:00Mackenzie J. Thompson et al.Structural basis for excitatory neuropeptide signalinghttps://www.nature.com/articles/s41594-023-01198-y2024-02-09T00:00:00+00:002024-02-09T00:00:00+00:00Valeria Kalienkova et al.Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channelhttps://www.nature.com/articles/s41467-023-44366-w2024-01-02T00:00:00+00:002024-01-02T00:00:00+00:00Vikram Dalal et al.Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptorshttps://www.nature.com/articles/s41467-023-44058-52023-12-11T00:00:00+00:002023-12-11T00:00:00+00:00Jody Pacalon et al.High-throughput ligand profile characterization in novel cell lines expressing seven heterologous insect olfactory receptors for the detection of volatile plant biomarkershttps://www.nature.com/articles/s41598-023-47455-42023-12-08T00:00:00+00:002023-12-08T00:00:00+00:00Katalin Zboray et al.Structural insights into the allosteric inhibition of P2X4 receptorshttps://www.nature.com/articles/s41467-023-42164-y2023-10-13T00:00:00+00:002023-10-13T00:00:00+00:00Cheng Shen et al.Asymmetric gating of a human hetero-pentameric glycine receptorhttps://www.nature.com/articles/s41467-023-42051-62023-10-11T00:00:00+00:002023-10-11T00:00:00+00:00Xiaofen Liu et al.Chronic cough relief by allosteric modulation of P2X3 without taste disturbancehttps://www.nature.com/articles/s41467-023-41495-02023-09-20T00:00:00+00:002023-09-20T00:00:00+00:00Chang-Run Guo et al.Modulation of GluA2–γ5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2https://www.nature.com/articles/s41594-023-01080-x2023-08-31T00:00:00+00:002023-08-31T00:00:00+00:00Shanti Pal Gangwar et al.Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayerhttps://www.nature.com/articles/s41598-023-38640-62023-07-15T00:00:00+00:002023-07-15T00:00:00+00:00Andras Szollosi et al.Physiologically relevant acid-sensing ion channel (ASIC) 2a/3 heteromers have a 1:2 stoichiometryhttps://www.nature.com/articles/s42003-023-05087-42023-07-08T00:00:00+00:002023-07-08T00:00:00+00:00Leon Fischer et al.Structural interplay of anesthetics and paralytics on muscle nicotinic receptorshttps://www.nature.com/articles/s41467-023-38827-52023-06-01T00:00:00+00:002023-06-01T00:00:00+00:00Umang Goswami et al.Derepression may masquerade as activation in ligand-gated ion channelshttps://www.nature.com/articles/s41467-023-36770-z2023-04-05T00:00:00+00:002023-04-05T00:00:00+00:00Christian J. G. Tessier et al.Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeuticshttps://www.nature.com/articles/s41467-023-37259-52023-03-25T00:00:00+00:002023-03-25T00:00:00+00:00Danyang Zhang et al.Conformational transitions and allosteric modulation in a heteromeric glycine receptorhttps://www.nature.com/articles/s41467-023-37106-72023-03-13T00:00:00+00:002023-03-13T00:00:00+00:00Eric Gibbs et al.Origin of acetylcholine antagonism in ELIC, a bacterial pentameric ligand-gated ion channelhttps://www.nature.com/articles/s42003-022-04227-62022-11-18T00:00:00+00:002022-11-18T00:00:00+00:00Mykhaylo Slobodyanyuk et al.Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulationhttps://www.nature.com/articles/s41467-022-34813-52022-11-17T00:00:00+00:002022-11-17T00:00:00+00:00John T. Petroff II et al.Conformational motions and ligand-binding underlying gating and regulation in IP3R channelhttps://www.nature.com/articles/s41467-022-34574-12022-11-14T00:00:00+00:002022-11-14T00:00:00+00:00Guizhen Fan et al.Structural basis for the activation of the lipid scramblase TMEM16Fhttps://www.nature.com/articles/s41467-022-34497-x2022-11-05T00:00:00+00:002022-11-05T00:00:00+00:00Melanie Arndt et al.Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscshttps://www.nature.com/articles/s41467-022-32594-52022-08-18T00:00:00+00:002022-08-18T00:00:00+00:00Arvind Kumar et al.The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptorshttps://www.nature.com/articles/s41467-022-32174-72022-08-04T00:00:00+00:002022-08-04T00:00:00+00:00Mieke Nys et al.Two-pore channel blockade by phosphoinositide kinase inhibitors YM201636 and PI-103 determined by a histidine residue near pore-entrancehttps://www.nature.com/articles/s42003-022-03701-52022-07-23T00:00:00+00:002022-07-23T00:00:00+00:00Canwei Du et al.Structural mechanism of muscle nicotinic receptor desensitization and block by curarehttps://www.nature.com/articles/s41594-022-00737-32022-03-17T00:00:00+00:002022-03-17T00:00:00+00:00Md. Mahfuzur Rahman et al.Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptorhttps://www.nature.com/articles/s41467-022-28400-x2022-02-10T00:00:00+00:002022-02-10T00:00:00+00:00Vasyl Bondarenko et al.Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptorhttps://www.nature.com/articles/s41467-022-28404-72022-02-08T00:00:00+00:002022-02-08T00:00:00+00:00Beatriz Herguedas et al.P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cellshttps://www.nature.com/articles/s41419-021-04378-02021-11-16T00:00:00+00:002021-11-16T00:00:00+00:00Anna Pegoraro et al.Structural determinants and regulation of spontaneous activity in GABAA receptorshttps://www.nature.com/articles/s41467-021-25633-02021-09-15T00:00:00+00:002021-09-15T00:00:00+00:00Craig A. Sexton et al.Allosteric coupling of sub-millisecond clamshell motions in ionotropic glutamate receptor ligand-binding domainshttps://www.nature.com/articles/s42003-021-02605-02021-09-09T00:00:00+00:002021-09-09T00:00:00+00:00Suhaila Rajab et al.Strictly regulated agonist-dependent activation of AMPA-R is the key characteristic of TAK-653 for robust synaptic responses and cognitive improvementhttps://www.nature.com/articles/s41598-021-93888-02021-07-15T00:00:00+00:002021-07-15T00:00:00+00:00Atsushi Suzuki et al.cAMP binding to closed pacemaker ion channels is non-cooperativehttps://www.nature.com/articles/s41586-021-03686-x2021-06-30T00:00:00+00:002021-06-30T00:00:00+00:00David S. White et al.