Kidney articles from across Nature Portfolio

Cisplatin, a chemotherapy drug, can cause long-lasting kidney injury. The authors explore miRNA:mRNA interactions in cisplatin-injured kidneys and find that such a cisplatin inducible miRNA as miR-429-3p suppresses the catabolism of branched-chain amino acids, leading to stimulation of ferroptotic cell death.

Cell metabolism plays pivotal roles during kidney embryogenesis. This research shows that glycolysis modulation affects nephron progenitor cells via Acetyl-CoA-modulated pathways, influencing both kidney development, and nephron endowment at birth.

New research provides insights into the mechanisms underlying the renal protective effects of sodium glucose cotransporter 2 inhibitors in lupus nephritis.

In a ground-breaking development, rat kidneys have been cryopreserved for an unprecedented duration of 100 days and subsequently transplanted successfully after nano-rewarming. This extraordinary achievement opens new possibilities for the field of organ banking.

A lack of federal access to health-care resources for undocumented immigrants in the USA has led to variability in access to health care — including dialysis — across states. Transforming dialysis care for these individuals is justified both on humanitarian and economic grounds, but requires a roadmap for advocacy and stakeholder engagement.

Kooman outlines the findings of a Communications Medicine article on deep learning-based detection of chronic kidney disease using ECGs. The author interprets the study’s findings in light of its limitations and outlines key considerations in the clinical implementation of such an approach.