Ion channels in the nervous system articles within Scientific Reports

Featured

• Article
  20 April 2024 | Open Access

  Interleukin-1α links peripheral Ca_V2.2 channel activation to rapid adaptive increases in heat sensitivity in skin

  • Anne-Mary N. Salib
  • , Meredith J. Crane
  •  & Diane Lipscombe

• Article
  03 April 2024 | Open Access

  Cloning, functional expression, and pharmacological characterization of inwardly rectifying potassium channels (Kir) from Apis mellifera

  • Fabien Sourisseau
  • , Chaimaa Chahine
  •  & Mohamed Chahine

• Article
  19 February 2024 | Open Access

  Clemastine and metformin extend the window of NMDA receptor surface expression in ageing oligodendrocyte precursor cells

  • Yasmine Kamen
  • , Kimberley Anne Evans
  •  & Ragnhildur Thóra Káradóttir

• Article
  09 February 2024 | Open Access

  Developmental loss of NMDA receptors results in supernumerary forebrain neurons through delayed maturation of transit-amplifying neuroblasts

  • Amalia J. Napoli
  • , Stephanie Laderwager
  •  & Howard I. Sirotkin

• Article
  09 February 2024 | Open Access

  Drosophila expressing mutant human KCNT1 transgenes make an effective tool for targeted drug screening in a whole animal model of KCNT1-epilepsy

  • Rashid Hussain
  • , Chiao Xin Lim
  •  & Leanne M. Dibbens

• Article
  28 January 2024 | Open Access

  Molecular determinants of ASIC1 modulation by divalent cations

  • Yi Liu
  • , Jichun Ma
  •  & Michael P. Maher

• Article
  27 October 2023 | Open Access

  Molecular mechanisms of NMDA excitotoxicity in the retina

  • Galina Dvoriantchikova
  • , Michelle Fleishaker
  •  & Dmitry Ivanov

• Article
  23 September 2023 | Open Access

  Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma

  • Wendy W. Liu
  • , Tyler G. Kinzy
  •  & Donald J. Zack

• Article
  01 June 2023 | Open Access

  Heterogeneity of voltage gated sodium current density between neurons decorrelates spiking and suppresses network synchronization in Scn1b null mouse models

  • Jacob M. Hull
  • , Nicholas Denomme
  •  & Lori L. Isom

• Article
  13 April 2023 | Open Access

  Increasing cell culture density during a developmental window prevents fated rod precursors derailment toward hybrid rod-glia cells

  • Ivana Barravecchia
  • , Chiara De Cesari
  •  & Gian Carlo Demontis

• Article
  21 February 2023 | Open Access

  The influence of astrocytic leaflet motility on ionic signalling and homeostasis at active synapses

  • Marinus Toman
  • , John Joseph Wade
  •  & Liam McDaid

• Article
  04 February 2023 | Open Access

  Nicotine exposure decreases likelihood of SARS-CoV-2 RNA expression and neuropathology in the hACE2 mouse brain but not moribundity

  • Ayland C. Letsinger
  • , James M. Ward
  •  & Jerrel L. Yakel

• Article
  22 December 2022 | Open Access

  Neuronal deletion of Ca_V1.2 is associated with sex-specific behavioral phenotypes in mice

  • Annette J. Klomp
  • , Ashley Plumb
  •  & Aislinn J. Williams

• Article
  15 November 2022 | Open Access

  Binding epitope for recognition of human TRPM4 channel by monoclonal antibody M4M

  • Shunhui Wei
  • , Julian Behn
  •  & Ping Liao

• Article
  06 October 2022 | Open Access

  Anti-hyperalgesic effects of photobiomodulation therapy (904 nm) on streptozotocin-induced diabetic neuropathy imply MAPK pathway and calcium dynamics modulation

  • Willians Fernando Vieira
  • , Kauê Franco Malange
  •  & Carlos Amilcar Parada

• Article
  08 September 2022 | Open Access

  Tau isoform-specific enhancement of L-type calcium current and augmentation of afterhyperpolarization in rat hippocampal neurons

  • Georgiana F. Stan
  • , Timothy W. Church
  •  & Neil V. Marrion

• Article
  15 June 2022 | Open Access

  TGR5 agonists induce peripheral and central hypersensitivity to bladder distension

  • Ashlee Caldwell
  • , Luke Grundy
  •  & Stuart M. Brierley

• Article
  02 June 2022 | Open Access

  Complex effects on Ca_V2.1 channel gating caused by a CACNA1A variant associated with a severe neurodevelopmental disorder

  • Benjamin J. Grosso
  • , Audra A. Kramer
  •  & Roger A. Bannister

• Article
  28 April 2022 | Open Access

  Dopamine influences attentional rate modulation in Macaque posterior parietal cortex

  • Jochem van Kempen
  • , Christian Brandt
  •  & Alexander Thiele

• Article
  09 April 2022 | Open Access

  A glibenclamide-sensitive TRPM4-mediated component of CA1 excitatory postsynaptic potentials appears in experimental autoimmune encephalomyelitis

  • Brenna C. Fearey
  • , Lars Binkle
  •  & Christine E. Gee

• Article
  07 April 2022 | Open Access

  Loss of β4-spectrin impairs Na_v channel clustering at the heminode and temporal fidelity of presynaptic spikes in developing auditory brain

  • Kaila Nip
  • , Sean Kashiwagura
  •  & Jun Hee Kim

• Article
  24 February 2022 | Open Access

  Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease

  • Lina A. Matschke
  • , Marlene A. Komadowski
  •  & Niels Decher

• Article
  20 December 2021 | Open Access

  Contributions of Na_V1.8 and Na_V1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons

  • Matthew Alsaloum
  • , Julie I. R. Labau
  •  & Stephen G. Waxman

• Article
  26 October 2021 | Open Access

  Preventing adolescent synaptic pruning in mouse prelimbic cortex via local knockdown of α4βδ GABA_A receptors increases anxiety response in adulthood

  • Matthew R. Evrard
  • , Michael Li
  •  & Sheryl S. Smith

• Article
  06 October 2021 | Open Access

  Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers

  • Adam J. Davenport
  • , Ioana Neagoe
  •  & Oliver M. Fischer

• Article
  02 September 2021 | Open Access

  Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission

  • Anna Kreis
  • , Jana Desloovere
  •  & Philippe Gailly

• Article
  02 August 2021 | Open Access

  Nerve growth factor and glutamate increase the density and expression of substance P-containing nerve fibers in healthy human masseter muscles

  • Abdelrahman M. Alhilou
  • , Akiko Shimada
  •  & Nikolaos Christidis

• Article
  07 June 2021 | Open Access

  SNP rs10420324 in the AMPA receptor auxiliary subunit TARP γ-8 regulates the susceptibility to antisocial personality disorder

  • Shi-Xiao Peng
  • , Yue-Ying Wang
  •  & Yun Stone Shi

• Article
  27 April 2021 | Open Access

  Altered neural oscillations and behavior in a genetic mouse model of NMDA receptor hypofunction

  • David D. Aguilar
  • , Leana K. Radzik
  •  & James M. McNally

• Article
  14 April 2021 | Open Access

  Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2.1

  • Mark L. Dallas
  • , Moza M. Al-Owais
  •  & Chris Peers

• Article
  25 March 2021 | Open Access

  The difficulty to model Huntington’s disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells

  • Kim Le Cann
  • , Alec Foerster
  •  & Angelika Lampert

• Article
  09 March 2021 | Open Access

  ATP signaling in the integrative neural center of Aplysia californica

  • János Györi
  • , Andrea B. Kohn
  •  & Leonid L. Moroz

• Article
  05 March 2021 | Open Access

  RNA-seq and GSEA identifies suppression of ligand-gated chloride efflux channels as the major gene pathway contributing to form deprivation myopia

  • Loretta Giummarra Vocale
  • , Sheila Crewther
  •  & David Crewther

• Article
  18 February 2021 | Open Access

  Retinal ganglion cell dysfunction in mice following acute intraocular pressure is exacerbated by P2X7 receptor knockout

  • Anna Y. M. Wang
  • , Vickie H. Y. Wong
  •  & Erica L. Fletcher

• Article
  26 January 2021 | Open Access

  Chronic BDNF simultaneously inhibits and unmasks superficial dorsal horn neuronal activity

  • Sascha R. A. Alles
  • , Max A. Odem
  •  & Peter A. Smith

• Article
  21 January 2021 | Open Access

  Neonicotinoids disrupt memory, circadian behaviour and sleep

  • Kiah Tasman
  • , Sergio Hidalgo
  •  & James J. L. Hodge

• Article
  18 January 2021 | Open Access

  Enhancement of parvalbumin interneuron-mediated neurotransmission in the retrosplenial cortex of adolescent mice following third trimester-equivalent ethanol exposure

  • Clark W. Bird
  • , Glenna J. Chavez
  •  & C. Fernando Valenzuela

• Article
  15 January 2021 | Open Access

  Biodistribution and radiation dosimetry of the positron emission tomography probe for AMPA receptor, [¹¹C]K-2, in healthy human subjects

  • Mai Hatano
  • , Tomoyuki Miyazaki
  •  & Takuya Takahashi

• Article
  08 January 2021 | Open Access

  A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability

  • Magdalena Nikolaeva-Koleva
  • , Laura Butron
  •  & Antonio Ferrer-Montiel

• Article
  10 December 2020 | Open Access

  Unravelling the intricate cooperativity of subunit gating in P2X2 ion channels

  • Christian Sattler
  • , Thomas Eick
  •  & Klaus Benndorf

• Article
  29 October 2020 | Open Access

  The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors

  • Kristyna Skrenkova
  • , Jae-man Song
  •  & Martin Horak

• Article
  22 October 2020 | Open Access

  Characterization of rare spindle and root cell transcriptional profiles in the stria vascularis of the adult mouse cochlea

  • Shoujun Gu
  • , Rafal Olszewski
  •  & Michael Hoa

• Article
  06 October 2020 | Open Access

  Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs

  • Max Bernhard
  •  & Bodo Laube

• Article
  02 September 2020 | Open Access

  Ca²⁺-activated KCa3.1 potassium channels contribute to the slow afterhyperpolarization in L5 neocortical pyramidal neurons

  • M. V. Roshchin
  • , V. N. Ierusalimsky
  •  & E. S. Nikitin

• Article
  13 August 2020 | Open Access

  Different functions of two putative Drosophila α₂δ subunits in the same identified motoneurons

  • Laurin Heinrich
  •  & Stefanie Ryglewski

• Article
  04 August 2020 | Open Access

  Differential effects of ethanol on behavior and GABA_A receptor expression in adult zebrafish (Danio rerio) with alternative stress coping styles

  • Alexander C. Goodman
  •  & Ryan Y. Wong

• Article
  28 July 2020 | Open Access

  Cholesterol modulates presynaptic and postsynaptic properties of excitatory synaptic transmission

  • Miloslav Korinek
  • , Inmaculada M. Gonzalez-Gonzalez
  •  & Ladislav Vyklicky

• Article
  20 July 2020 | Open Access

  Endogenous neurotoxin-like protein Ly6H inhibits alpha7 nicotinic acetylcholine receptor currents at the plasma membrane

  • Yasuhiro Moriwaki
  • , Natsuki Kubo
  •  & Hidemi Misawa

• Article
  09 July 2020 | Open Access

  Regional transcriptome analysis of AMPA and GABA_A receptor subunit expression generates E/I signatures of the human brain

  • Kevin Shen
  • , Tommaso Zeppillo
  •  & Agenor Limon

• Article
  22 June 2020 | Open Access

  Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA_A receptors

  • Christina Birkedahl Falk-Petersen
  • , Tsonko M. Tsonkov
  •  & Petrine Wellendorph