Integrins articles from across Nature Portfolio

Integrins are transmembrane glycoproteins that mediate attachment of cells to the extracellular matrix or to other cells via interactions with proteins such as fibronectin and collagen. Integrins also transmit signals from outside to inside the cell by regulating receptor tyrosine kinase signalling. Integrins are heterodimers of different α- and β-subunits.

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