Inhibitory RNA techniques
Inhibitory RNA techniques are methods that use engineered RNA molecules to inhibit gene expression. Various approaches, including the expression or injection of microRNA, short inhibiting RNA, double-stranded or antisense RNA (e.g. morpholino oligomers), work via mechanisms that include transcript cleavage, sequestration and the inhibition of protein translation.
Latest Research and Reviews
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Research
| Open Access
Global identification of functional microRNA-mRNA interactions in Drosophila
Nature Communications 10, 1626 -
Research
| Open Access
The autosomal Gsdf gene plays a role in male gonad development in Chinese tongue sole (Cynoglossus semilaevis)
Scientific Reports 8, 17716
Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells
LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C
Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes
Regulation of the expression of nine antimicrobial peptide genes by TmIMD confers resistance against Gram-negative bacteria
Global identification of functional microRNA-mRNA interactions in Drosophila
The autosomal Gsdf gene plays a role in male gonad development in Chinese tongue sole (Cynoglossus semilaevis)
CRISPR unveils T-cell-resistance mechanisms in tumours