Infectious-disease diagnostics

Infectious-disease diagnostics is the procedure by which the causative agent of an infectious disease is identified and often characterized. It can be based solely on clinical presentation or more rigorous diagnostic tests, such as culturing of the infectious agent, microscopy, biochemical screens and molecular methods.

Latest Research and Reviews

News and Comment

  • Comments and Opinion |

    Researchers starting clinical trials of prevention measures for COVID-19 have a unique window of opportunity for collecting blood from the participants, at baseline and at the end of the trial, to be able to incorporate critical data into their analysis once serological tests for the causative coronavirus become available.

    • Marc Lipsitch
    • , Rebecca Kahn
    •  & Michael J. Mina
    Nature Medicine 26, 818-819
  • News and Views |

    Since the emergence of methicillin-resistant Staphylococcus aureus 60 years ago, scientists have been trying to engineer β-lactam antibiotics to restore drug susceptibility. Genomic data now shows that clavulanic acid (a β-lactamase inhibitor) can restore susceptibility in many strains, but only if they carry key mutations.

    • Fergus Hamilton
    •  & Alasdair MacGowan
    Nature Microbiology 4, 1604-1605
  • Comments and Opinion |

    Late presentation to hepatitis B virus and hepatitis C virus care is common, hindering global efforts to reduce the morbidity and mortality associated with liver disease. Models of care promoting and simplifying early testing of viral hepatitis are needed if we are to eliminate viral hepatitis as a major public health threat by 2030.

    • Jeffrey V. Lazarus
    • , Camila Picchio
    • , John F. Dillon
    • , Jürgen K. Rockstroh
    • , Nina Weis
    •  & Maria Buti