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| Open AccessNon-Invasive MRI of Blood–Cerebrospinal Fluid Barrier Function
The blood–cerebrospinal fluid barrier (BCSFB) is an important interface for brain homeostasis. Here the authors describe a non-invasive MRI technique for the quantitative assessment of BCSFB function.
- P. G. Evans
- , M. Sokolska
- & J. A. Wells
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| Open AccessYap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus
Failure of the ependymal cell layer that lines the ventricular surfaces of the brain can result in fetal hydrocephalus. Park et al. reveal a role for the Hippo pathway gene Yap in the generation of ependymal cells, and show that suppression of Yap is observed in a model of hydrocephalus.
- Raehee Park
- , Uk Yeol Moon
- & Seonhee Kim