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Article
| Open Access
Iterative pseudo balancing for stem cell microscopy image classification
- Adam Witmer
- & Bir Bhanu
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Article
| Open Access
Attenuated huntingtin gene CAG nucleotide repeat size in individuals with Lynch syndrome
- Karin Dalene Skarping
- , Larissa Arning
- & Samuel Gebre-Medhin
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| Open Access
Retinal dysfunction in Huntington’s disease mouse models concurs with local gliosis and microglia activation
- Fátima Cano-Cano
- , Francisco Martín-Loro
- & Luis M. Valor
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Article
| Open Access
Dose-dependent reduction of somatic expansions but not Htt aggregates by di-valent siRNA-mediated silencing of MSH3 in HdhQ111 mice
- Rachelle Driscoll
- , Lucas Hampton
- & Andreas Weihofen
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Article
| Open Access
Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington’s disease
- Mohit H. Adhikari
- , Tamara Vasilkovska
- & Marleen Verhoye
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| Open Access
Quantifying mutant huntingtin protein in human cerebrospinal fluid to support the development of huntingtin-lowering therapies
- Stephanie Vauleon
- , Katharina Schutz
- & David J. Hawellek
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| Open Access
Beneficial behavioral effects of chronic cerebral dopamine neurotrophic factor (CDNF) infusion in the N171-82Q transgenic model of Huntington’s disease
- P. Stepanova
- , D. Kumar
- & M. H. Voutilainen
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Article
| Open Access
Salivary Huntingtin protein is uniquely associated with clinical features of Huntington’s disease
- Georgia M. Parkin
- , Jody Corey-Bloom
- & Elizabeth A. Thomas
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| Open Access
Forecasting individual progression trajectories in Huntington disease enables more powered clinical trials
- Igor Koval
- , Thomas Dighiero-Brecht
- & Alexandra Durr
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| Open Access
Lumbar puncture safety and tolerability in premanifest and manifest Huntington’s disease: a multi-analysis cross-sectional study
- Yara Refaat Hassan
- , Filipe Brogueira Rodrigues
- & Sarah J. Tabrizi
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Article
| Open Access
A hierarchical Bayesian entry time realignment method to study the long-term natural history of diseases
- Liangbo L. Shen
- , Lucian V. Del Priore
- & Joshua L. Warren
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| Open Access
Kinematics and observer-animator kinematic similarity predict mental state attribution from Heider–Simmel style animations
- Bianca A. Schuster
- , Dagmar S. Fraser
- & Jennifer L. Cook
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| Open Access
Multiparametric characterization of white matter alterations in early stage Huntington disease
- Isaac M. Adanyeguh
- , Francesca Branzoli
- & Fanny Mochel
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| Open Access
The heat shock response, determined by QuantiGene multiplex, is impaired in HD mouse models and not caused by HSF1 reduction
- Casandra Gomez-Paredes
- , Michael A. Mason
- & Gillian P. Bates
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Article
| Open Access
A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity
- Houda G. Khaled
- , Hongxuan Feng
- & Russell L. Margolis
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Article
| Open AccessHair and salivary cortisol and their relationship with lifestyle, mood and cognitive outcomes in premanifest Huntington’s disease
- Travis Cruickshank
- , Tenielle Porter
- & Danielle M. Bartlett
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| Open Access
Brain-derived neurotrophic factor in cerebrospinal fluid and plasma is not a biomarker for Huntington’s disease
- Zhen-Yi Andy Ou
- , Lauren M. Byrne
- & Edward J. Wild
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Article
| Open Access
Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse model
- M. J. Vijay Kumar
- , Devanshi Shah
- & James P. Clement
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| Open Access
Analysis of mutant and total huntingtin expression in Huntington’s disease murine models
- Valentina Fodale
- , Roberta Pintauro
- & Alberto Bresciani
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| Open Access
Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington’s disease patients
- C. Y. Daniel Lee
- , Nan Wang
- & X. William Yang
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| Open Access
Cerebral dopamine neurotrophic factor (CDNF) protects against quinolinic acid-induced toxicity in in vitro and in vivo models of Huntington’s disease
- P. Stepanova
- , V. Srinivasan
- & M. H. Voutilainen
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Article
| Open Access
Increased intestinal permeability and gut dysbiosis in the R6/2 mouse model of Huntington’s disease
- Tiberiu Loredan Stan
- , Rana Soylu-Kucharz
- & Maria Björkqvist
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Article
| Open Access
Fiberoptic endoscopic evaluation of swallowing in early-to-advanced stage Huntington’s disease
- Antonio Schindler
- , Nicole Pizzorni
- & Andrea Ciammola
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| Open Access
Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders
- Chun-Hwei Tai
- , Ming-Kai Pan
- & Chung-Chin Kuo
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| Open Access
Intra-striatal AAV2.retro administration leads to extensive retrograde transport in the rhesus macaque brain: implications for disease modeling and therapeutic development
- Alison R. Weiss
- , William A. Liguore
- & Jodi L. McBride
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| Open Access
A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models
- Javier Ganz
- , Talya Shacham
- & Gerardo Z. Lederkremer
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| Open Access
Resting-state connectivity stratifies premanifest Huntington’s disease by longitudinal cognitive decline rate
- Pablo Polosecki
- , Eduardo Castro
- & Guillermo A. Cecchi
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| Open Access
Assessing average somatic CAG repeat instability at the protein level
- Hubert Aviolat
- , Ricardo Mouro Pinto
- & Marian DiFiglia
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| Open Access
Transcriptional correlates of the pathological phenotype in a Huntington’s disease mouse model
- Andrea Gallardo-Orihuela
- , Irati Hervás-Corpión
- & Luis M. Valor
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| Open Access
Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington’s disease
- Elaine E. Irvine
- , Loukia Katsouri
- & Dominic J. Withers
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Article
| Open Access
Extensive Expression Analysis of Htt Transcripts in Brain Regions from the zQ175 HD Mouse Model Using a QuantiGene Multiplex Assay
- Aikaterini S. Papadopoulou
- , Casandra Gomez-Paredes
- & Gillian P. Bates
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| Open Access
Peripheral Expression of Mutant Huntingtin is a Critical Determinant of Weight Loss and Metabolic Disturbances in Huntington’s Disease
- Priya Lakra
- , Kumari Aditi
- & Namita Agrawal
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Article
| Open Access
Molecular mechanisms of heterogeneous oligomerization of huntingtin proteins
- Silvia Bonfanti
- , Maria Chiara Lionetti
- & Caterina A. M. La Porta
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| Open Access
Inhibition of tumour necrosis factor alpha in the R6/2 mouse model of Huntington’s disease by etanercept treatment
- Jeffrey Pido-Lopez
- , Benedict Tanudjojo
- & Gillian P. Bates
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Article
| Open Access
Mutant huntingtin disturbs circadian clock gene expression and sleep patterns in Drosophila
- Anikó Faragó
- , Nóra Zsindely
- & László Bodai
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Article
| Open Access
Cortical circuit alterations precede motor impairments in Huntington’s disease mice
- Johanna Burgold
- , Elena Katharina Schulz-Trieglaff
- & Irina Dudanova
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| Open Access
Alterations in the tyrosine and phenylalanine pathways revealed by biochemical profiling in cerebrospinal fluid of Huntington’s disease subjects
- Stephanie Herman
- , Valter Niemelä
- & Kim Kultima
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Article
| Open Access
Striatal Interneurons in Transgenic Nonhuman Primate Model of Huntington’s Disease
- Shoeb B. Lallani
- , Rosa M. Villalba
- & Anthony W. S. Chan
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| Open Access
Antagonistic pleiotropy in mice carrying a CAG repeat expansion in the range causing Huntington’s disease
- A. J. Morton
- , E. A. Skillings
- & Z. Zheng
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Article
| Open Access
EEG may serve as a biomarker in Huntington’s disease using machine learning automatic classification
- Omar F. F. Odish
- , Kristinn Johnsen
- & J. Gert van Dijk
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Article
| Open Access
Computerised Dynamic Posturography in Premanifest and Manifest individuals with Huntington’s Disease
- Alvaro Reyes
- , Danielle Salomonczyk
- & Travis Cruickshank
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Article
| Open Access
In vivo neutralization of the protagonist role of macrophages during the chronic inflammatory stage of Huntington’s disease
- Jeffrey Pido-Lopez
- , Ralph Andre
- & Gillian P. Bates
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Article
| Open Access
Early alteration of epigenetic-related transcription in Huntington’s disease mouse models
- Irati Hervás-Corpión
- , Deisy Guiretti
- & Luis M. Valor
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Article
| Open Access
Comparative Analysis of Mutant Huntingtin Binding Partners in Yeast Species
- Yanding Zhao
- , Ashley A. Zurawel
- & Surachai Supattapone
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Article
| Open Access
Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington’s Disease
- Ana I. Duarte
- , Marie Sjögren
- & Maria Björkqvist
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Article
| Open Access
A human huntingtin SNP alters post-translational modification and pathogenic proteolysis of the protein causing Huntington disease
- D. D. O. Martin
- , C. Kay
- & M. R. Hayden
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Article
| Open Access
Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease
- Arianna Novati
- , Thomas Hentrich
- & Julia M. Schulze-Hentrich
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Article
| Open Access
Cerebrospinal fluid neurogranin and TREM2 in Huntington’s disease
- Lauren M. Byrne
- , Filipe B. Rodrigues
- & Edward J. Wild
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Article
| Open Access
Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools
- Shawn Minnig
- , Robert M. Bragg
- & Jeffrey B. Carroll
External evaluation of a deep learning-based approach for automated brain volumetry in patients with huntington’s disease