Herpes virus articles from across Nature Portfolio

Two recent papers implicate Epstein–Barr virus (EBV) as a trigger for the development of multiple sclerosis and provide mechanistic insights into EBV-mediated development of the disease.

This study provides insights into the neuroinvasive mechanism of neurotropic alphaherpesviruses, which involves viral assimilation and repurposing of a cellular motor protein.

This study reports the development of a CRISPR –Cas9 therapeutic to target herpes simplex virus 1 and treat herpetic stromal keratitis in mice.

This paper found that cytoplasmic control of intranuclear polarity by human cytomegalovirus leads to segregation of viral DNA from heterochromatin, thus promoting virus replication.

Topical administration of aminoglycoside antibiotics has been shown to induce expression of interferon-stimulated genes in dendritic cells, inducing an antiviral state in the vaginal and lung mucosa that increases resistance to infection with herpes simplex virus 1, influenza and Zika viruses.