Nature

Hepatic encephalopathy articles from across Nature Portfolio

Hepatic encephalopathy is altered brain function specifically associated with severe liver disease and liver failure. The condition occurs because of the accumulation of toxic substances or waste products (ammonia) in the bloodstream that are normally removed by the liver. Clinical features can include confusion, altered levels of consciousness and coma.

Latest Research and Reviews

Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease
- Veronika Rackayova
- Olivier Braissant
- Valérie A. McLin
ResearchOpen Access05 May 2020 Scientific Reports
Volume: 10, P: 7536
Minimal Hepatic Encephalopathy is Associated with Increased Cerebral Vascular Resistance. A Transcranial Doppler Ultrasound Study
- Francesca Romana Ponziani
- Barbara Funaro
- Maria Assunta Zocco
ResearchOpen Access25 Oct 2019 Scientific Reports
Volume: 9, P: 15373
Validation of the Korean Stroop Test in Diagnosis of Minimal Hepatic Encephalopathy
- Eileen L. Yoon
- Dae Won Jun
- Hokyoung Ryu
ResearchOpen Access29 May 2019 Scientific Reports
Volume: 9, P: 8027
Benefits of Early Treatment for Patients with Hepatic Myelopathy Secondary to TIPS: A Retrospective Study in Northern China
- Hongwei Zhao
- Zhendong Yue
- Fuquan Liu
ResearchOpen Access12 Oct 2018 Scientific Reports
Volume: 8, P: 15184
Repeated Measures of Blood and Breath Ammonia in Response to Control, Moderate and High Protein Dose in Healthy Men
- Lisa A. Spacek
- Arthur Strzepka
- Steven F. Solga
ResearchOpen Access07 Feb 2018 Scientific Reports
Volume: 8, P: 2554
Role of per-rectal portal scintigraphy in long-term follow-up of congenital portosystemic shunt
- Yuki Cho
- Daisuke Tokuhara
- Haruo Shintaku
Research31 Jan 2014 Pediatric Research
Volume: 75, P: 658-662

All Research & Reviews

News and Comment

Inside the USCAP Journals

Comments & Opinion29 Jul 2015 Laboratory Investigation
Volume: 95, P: 844-845
Engineered microbes treat experimental hyperammonemia

Research Highlights21 Jul 2015 Nature Reviews Gastroenterology & Hepatology
Volume: 12, P: 428
The gut is a key target of therapy in hepatic encephalopathy

Little progress has been made in the pharmacological management of patients with hepatic encephalopathy, partly because it is difficult to perform clinical trials in this group of patients. A new clinical trial now suggests that polyethylene glycol is more effective than the current standard first-line therapy in these patients.
- Rohit Sawhney
- Rajiv Jalan
News & Views28 Oct 2014 Nature Reviews Gastroenterology & Hepatology
Volume: 12, P: 7-8
Long-term cognitive function improved in MHE after liver transplantation
- Claire Greenhill
Research Highlights07 Feb 2012 Nature Reviews Gastroenterology & Hepatology
Volume: 9, P: 126
Intestinal inflammation—key to complications in cirrhosis?

An ideal diagnostic test should be quick, reliable and noninvasive. Fecal calprotectin is considered a marker of intestinal inflammation and has proven to be an effective test for IBD, but is fecal calprotectin a useful diagnostic tool when assessing patients with cirrhosis?
- Ravi K. Prakash
- Kevin D. Mullen
News & Views01 Nov 2011 Nature Reviews Gastroenterology & Hepatology
Volume: 8, P: 665-667
Prebiotics and probiotics show promise as a therapy for hepatic encephalopathy?
- Ezzie Hutchinson
Research Highlights01 Apr 2010 Nature Reviews Gastroenterology & Hepatology
Volume: 7, P: 184

All News & Comment

Search

Advanced search

Quick links