Health sciences

Definition

The health sciences study all aspects of health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.

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Latest Research and Reviews

  • Reviews |

    This Review discusses the latest findings and current theories on the pathogenesis of abdominal aortic aneurysm (AAA) and highlights potential medical therapies for AAA, summarizing previous, ongoing, and potential clinical trials of medical interventions for small AAAs. This expanding volume of research is expected to result in a range of novel medical therapies for AAA within the next decade.

    • Jonathan Golledge
  • Reviews |

    Bronchiectasis refers to dilatation in the bronchi, as detected by radiological examination. Often the result of other diseases, bronchiectasis is also a disease in its own right and can lead to chronic infections, inflammation, airway damage and, ultimately, reduced lung function and respiratory failure.

    • James D. Chalmers
    • , Anne B. Chang
    • , Sanjay H. Chotirmall
    • , Raja Dhar
    •  & Pamela J. McShane
  • Research |

    Transcriptomes of about 70,000 single cells from first-trimester deciduas and placentas reveal subsets of perivascular, stromal and natural killer cells in the decidua, with distinct immunomodulatory profiles that regulate the environment necessary for successful placentation.

    • Roser Vento-Tormo
    • , Mirjana Efremova
    • , Rachel A. Botting
    • , Margherita Y. Turco
    • , Miquel Vento-Tormo
    • , Kerstin B. Meyer
    • , Jong-Eun Park
    • , Emily Stephenson
    • , Krzysztof Polański
    • , Angela Goncalves
    • , Lucy Gardner
    • , Staffan Holmqvist
    • , Johan Henriksson
    • , Angela Zou
    • , Andrew M. Sharkey
    • , Ben Millar
    • , Barbara Innes
    • , Laura Wood
    • , Anna Wilbrey-Clark
    • , Rebecca P. Payne
    • , Martin A. Ivarsson
    • , Steve Lisgo
    • , Andrew Filby
    • , David H. Rowitch
    • , Judith N. Bulmer
    • , Gavin J. Wright
    • , Michael J. T. Stubbington
    • , Muzlifah Haniffa
    • , Ashley Moffett
    •  & Sarah A. Teichmann
    Nature 563, 347–353
  • Research |

    An immunoprecipitation-based protocol is developed to analyse DNA methylation in small quantities of circulating cell-free DNA, and can detect and classify cancers in plasma samples from several tumour types.

    • Shu Yi Shen
    • , Rajat Singhania
    • , Gordon Fehringer
    • , Ankur Chakravarthy
    • , Michael H. A. Roehrl
    • , Dianne Chadwick
    • , Philip C. Zuzarte
    • , Ayelet Borgida
    • , Ting Ting Wang
    • , Tiantian Li
    • , Olena Kis
    • , Zhen Zhao
    • , Anna Spreafico
    • , Tiago da Silva Medina
    • , Yadon Wang
    • , David Roulois
    • , Ilias Ettayebi
    • , Zhuo Chen
    • , Signy Chow
    • , Tracy Murphy
    • , Andrea Arruda
    • , Grainne M. O’Kane
    • , Jessica Liu
    • , Mark Mansour
    • , John D. McPherson
    • , Catherine O’Brien
    • , Natasha Leighl
    • , Philippe L. Bedard
    • , Neil Fleshner
    • , Geoffrey Liu
    • , Mark D. Minden
    • , Steven Gallinger
    • , Anna Goldenberg
    • , Trevor J. Pugh
    • , Michael M. Hoffman
    • , Scott V. Bratman
    • , Rayjean J. Hung
    •  & Daniel D. De Carvalho
    Nature, 1–5
  • Research |

    Introduction of a suicide gene together with a linked cell-division gene to generate a safe-cell system enables the selective elimination of proliferating cells after cell transplantation in mouse models of cell therapy.

    • Qin Liang
    • , Claudio Monetti
    • , Maria V. Shutova
    • , Eric J. Neely
    • , Sabiha Hacibekiroglu
    • , Huijuan Yang
    • , Christopher Kim
    • , Puzheng Zhang
    • , Chengjin Li
    • , Kristina Nagy
    • , Maria Mileikovsky
    • , Istvan Gyongy
    • , Hoon-Ki Sung
    •  & Andras Nagy
    Nature, 1–4

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