Glial stem cells articles from across Nature Portfolio

Functional and transcriptomic comparison of primary neonatal, adult and ESC-derived astrocytes reveals major variations, highlighting the importance for an informed choice of astrocyte origin for research questions.

Oligodendrocyte precursor cells (OPCs) have functions beyond oligodendrogenesis. Here the authors show that OPCs can engulf thalamocortical presynapses in response to sensory experience in mice.

There are no new oligodendrocytes in potentially remyelinated multiple sclerosis shadow plaques, although oligodendrocyte generation is increased in the normal appearing white matter of patients with aggressive disease, informing the development of new therapies.