Genomics

Genomics is the study of the full genetic complement of an organism (the genome). It employs recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyse the structure and function of genomes.

Latest Research and Reviews

News and Comment

  • Comments & Opinion |

    It has been 25 years since the release of GATTACA, a film that tells the story of a credible near future in which society’s inequalities, formerly associated with race and class, have been replaced with new prejudices based on genetic determinism. Here we compare GATTACA’s fictional technologies with reality’s state of the art, assessing the legal protections afforded in today’s society against GATTACA’s dystopian future in which personal freedom and privacy rights are substantially curtailed by genomic innovations. We further discuss how GATTACA’s prescient forewarnings are still relevant today in light of the current trajectory of genomic science and technology.

    • Dov Greenbaum
    •  & Mark Gerstein
  • Editorial |

    AI promises to bring many benefits to healthcare and research, but mistrust has built up owing to many instances of harm to under-represented communities. To amend this, participatory approaches can directly involve communities in AI research that will impact them. An important element of such approaches is ensuring that communities can take control over their own data and how they are shared.

  • Comments & Opinion |

    Indigenous peoples are under-represented in genomic datasets, which can lead to limited accuracy and utility of machine learning models in precision health. While open data sharing undermines rights of Indigenous communities to govern data decisions, federated learning may facilitate secure and community-consented data sharing.

    • Nima Boscarino
    • , Reed A. Cartwright
    •  & Krystal S. Tsosie