Genetics articles from across Nature Portfolio

Genetics is the branch of science concerned with genes, heredity, and variation in living organisms. It seeks to understand the process of trait inheritance from parents to offspring, including the molecular structure and function of genes, gene behaviour in the context of a cell or organism (e.g. dominance and epigenetics), gene distribution, and variation and change in populations.

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Strikingly convergent genome alterations in two independently evolved holoparasites

Two independently evolved lineages of holoparasites — Balanophora (Santalales) and Sapria (Malpighiales) — display massively convergent characteristics of genome modifications, including gene loss in major pathways, reduction of multigene families and generally relaxed selection pressure. These findings provide valuable new insights into the fascinating biology of parasitic plants.

News & Views21 Sept 2023 Nature Plants
P: 1-2
Using CRISPR to study gene function aids understanding of 22q11.2 deletion syndrome

Most high-throughput assays to investigate the role of genes in disease involve in vitro cell models. Now a technology that targets CRISPR–Cas9 gene editing to specific cells in mice, and analyses transcriptional effects in single nuclei, has led to fresh insights into the genes involved in 22q11.2 deletion syndrome.

News & Views20 Sept 2023 Nature
New resistance gene against maize rough dwarf disease identified in cereal crops

We identified ZmGLK36, a resistance gene against rice black-streaked dwarf virus (RBSDV), in maize. ZmGLK36 mediates resistance by regulating jasmonic acid (JA) biosynthesis and JA-mediated defence response; it also grants resistance to RBSDV to other cereal crops, such as rice and wheat.

News & Views19 Sept 2023 Nature Plants
P: 1-2

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Latest Research and Reviews

The epidemiological and genetic characteristics of human parvovirus B19 in patients with febrile rash illnesses in China
- Haoran Jiang
- Qi Qiu
- Xiaomei Li
ResearchOpen Access23 Sept 2023 Scientific Reports
Volume: 13, P: 15913
Curated incidence of lysosomal storage diseases from the Taiwan Biobank
- Meng-Ju Melody Tsai
- Miao-Zi Hung
- Wuh-Liang Hwu
ResearchOpen Access23 Sept 2023 npj Genomic Medicine
Volume: 8, P: 27
Integrated Transcriptome Analysis of Long Noncoding RNA and mRNA in Developing and Aging Mouse Retina
- Kangjie Kong
- Peiyuan Wang
- Shida Chen
ResearchOpen Access23 Sept 2023 Scientific Data
Volume: 10, P: 653
Distinct aneuploid evolution of astrocytoma and glioblastoma during recurrence
- Jinsen Zhang
- Yuan Feng
- Ying Mao
ResearchOpen Access23 Sept 2023 npj Precision Oncology
Volume: 7, P: 97
Epitranscriptomic subtyping, visualization, and denoising by global motif visualization

The current available tools lack the ability to accurately classify and visually represent epitranscriptomic profiling data. Here, the authors provide a framework that offers a general solution for the visualization and interpretation of such data.
- Jianheng Liu
- Tao Huang
- Rui Zhang
ResearchOpen Access23 Sept 2023 Nature Communications
Volume: 14, P: 5944
Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma
- Wendy W. Liu
- Tyler G. Kinzy
- Donald J. Zack
ResearchOpen Access23 Sept 2023 Scientific Reports
Volume: 13, P: 15871

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News and Comment

Methylation signatures in clinically variable syndromic disorders: a familial DNMT3A variant in two adults with Tatton-Brown–Rahman syndrome
- Candy Kumps
- Erika D’haenens
- Olivier M. Vanakker
Comments & Opinion22 Sept 2023 European Journal of Human Genetics
P: 1-5
Post-COVID-19 epigenetic signatures
- Laurie A. Dempsey
Research Highlights21 Sept 2023 Nature Immunology
P: 1
Strikingly convergent genome alterations in two independently evolved holoparasites

Two independently evolved lineages of holoparasites — Balanophora (Santalales) and Sapria (Malpighiales) — display massively convergent characteristics of genome modifications, including gene loss in major pathways, reduction of multigene families and generally relaxed selection pressure. These findings provide valuable new insights into the fascinating biology of parasitic plants.

News & Views21 Sept 2023 Nature Plants
P: 1-2
Genetic modification can improve crop yields — but stop overselling it

With a changing climate and a growing population, the world increasingly needs more-productive and resilient crops. But improving them requires a knowledge of what actually works in the field.
- Merritt Khaipho-Burch
- Mark Cooper
- Edward S. Buckler
Comments & Opinion20 Sept 2023 Nature
Volume: 621, P: 470-473
Using CRISPR to study gene function aids understanding of 22q11.2 deletion syndrome

Most high-throughput assays to investigate the role of genes in disease involve in vitro cell models. Now a technology that targets CRISPR–Cas9 gene editing to specific cells in mice, and analyses transcriptional effects in single nuclei, has led to fresh insights into the genes involved in 22q11.2 deletion syndrome.

News & Views20 Sept 2023 Nature
Predicting the effects of multigene perturbations

Roohani et al. have developed a deep learning tool called GEARS that predicts the effects of multigene perturbations.
- Henry Ertl
Research Highlights19 Sept 2023 Nature Reviews Genetics
P: 1

All News & Comment

Genetics articles from across Nature Portfolio

Featured

Strikingly convergent genome alterations in two independently evolved holoparasites

Using CRISPR to study gene function aids understanding of 22q11.2 deletion syndrome

New resistance gene against maize rough dwarf disease identified in cereal crops

Related Subjects

Latest Research and Reviews

The epidemiological and genetic characteristics of human parvovirus B19 in patients with febrile rash illnesses in China

Curated incidence of lysosomal storage diseases from the Taiwan Biobank

Integrated Transcriptome Analysis of Long Noncoding RNA and mRNA in Developing and Aging Mouse Retina

Distinct aneuploid evolution of astrocytoma and glioblastoma during recurrence

Epitranscriptomic subtyping, visualization, and denoising by global motif visualization

Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma

News and Comment

Methylation signatures in clinically variable syndromic disorders: a familial DNMT3A variant in two adults with Tatton-Brown–Rahman syndrome

Post-COVID-19 epigenetic signatures

Strikingly convergent genome alterations in two independently evolved holoparasites

Genetic modification can improve crop yields — but stop overselling it

Using CRISPR to study gene function aids understanding of 22q11.2 deletion syndrome

Predicting the effects of multigene perturbations

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