Genetic mapping articles from across Nature Portfolio

Genetic mapping is the process of determining the order of and relative distance between genetic markers (specific sequences or heritable elements that generate a phenotype) on a chromosome based on their pattern of inheritance. Genetic mapping in bacteria relies on chromosome transfer between cells.

Latest Research and Reviews

Research
09 September 2022 | Open Access

CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway

RNA has been implicated in DNA repair. This work shows that the interplay of RNAPII-generated nascent RNA, RNA:DNA hybrids and the resection factor CtIP guide DNA double strand break repair pathway choice towards error-free homologous recombination.
- Daniel Gómez-Cabello
- , George Pappas
- & Jiri Bartek
Nature Communications 13, 5303
Research | 05 April 2022

The genetic architecture underlying body-size traits plasticity over different temperatures and developmental stages in Caenorhabditis elegans
- Muhammad I. Maulana
- , Joost A. G. Riksen
- & Mark G. Sterken
Heredity 128, 313-324
Research
17 November 2021 | Open Access

SuperSelective primer pairs for sensitive detection of rare somatic mutations
- Fred Russell Kramer
- & Diana Yaneth Vargas
Scientific Reports 11, 22384
Research
01 November 2021 | Open Access

OBV (obscure vein), a C₂H₂ zinc finger transcription factor, positively regulates chloroplast development and bundle sheath extension formation in tomato (Solanum lycopersicum) leaf veins
- Jinghua Lu
- , Chunyang Pan
- & Junming Li
Horticulture Research 8, 230
Research
28 September 2021 | Open Access

The identification of grain size genes by RapMap reveals directional selection during rice domestication

Cloning quantitative trait loci (QTL) in crops is often slow and laborious. Here, the authors describe RapMap, a method to rapidly clone multiple QTL based on F₂ gradient populations coupled with a co-segregation standard, and show how it can be used to identify genes controlling grain size in rice.
- Juncheng Zhang
- , Dejian Zhang
- & Yibo Li
Nature Communications 12, 5673
Research
30 July 2021 | Open Access

Combining conventional QTL analysis and whole-exome capture-based bulk-segregant analysis provides new genetic insights into tuber sprout elongation and dormancy release in a diploid potato population
- Sanjeev Kumar Sharma
- , Karen McLean
- & Glenn J. Bryan
Heredity 127, 253-265

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News and Comment

Research Highlights | 30 April 2019

Imaging chromatin and RNA in embryos
- Rita Strack
Nature Methods 16, 361
Research Highlights | 30 October 2018

Diploid genome in 3D

Dip-C, a descendent of the 3C method, reveals 3D genome structures of single diploid human cells.
- Lei Tang
Nature Methods 15, 858
Research Highlights | 02 July 2018

Higher-order genetic interactions
- Nicole Rusk
Nature Methods 15, 481
Research Highlights | 01 December 2017

Haplobank of mutated mouse stem cell clones

Nature Methods 14, 1130
Editorial | 30 May 2017

CRISPR standards

With the ever-expanding use of CRISPR technology, the development of standards to quantitatively benchmark on- and off-target activity needs to keep pace.

Nature Methods 14, 541
Research Highlights | 18 October 2016

Accelerating towards mental illness
- Sian Lewis
Nature Reviews Neuroscience 17, 671

All News & Comment

Genetic mapping articles from across Nature Portfolio

Latest Research and Reviews

CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway

The genetic architecture underlying body-size traits plasticity over different temperatures and developmental stages in Caenorhabditis elegans

SuperSelective primer pairs for sensitive detection of rare somatic mutations

OBV (obscure vein), a C₂H₂ zinc finger transcription factor, positively regulates chloroplast development and bundle sheath extension formation in tomato (Solanum lycopersicum) leaf veins

The identification of grain size genes by RapMap reveals directional selection during rice domestication

Combining conventional QTL analysis and whole-exome capture-based bulk-segregant analysis provides new genetic insights into tuber sprout elongation and dormancy release in a diploid potato population

News and Comment

Imaging chromatin and RNA in embryos

Diploid genome in 3D

Higher-order genetic interactions

Haplobank of mutated mouse stem cell clones

CRISPR standards

Accelerating towards mental illness

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