Genetic hybridization articles from across Nature Portfolio

Analysis of 1,673 sequenced Saccharomyces cerevisiae isolates identifies 3,852 sequence blocks introgressed from Saccharomyces paradoxus, most of which are recent and clade-specific. By contrast, divergent Chinese strains of S. cerevisiae show little evidence of introgression but do share ancient polymorphisms with S. paradoxus due to incomplete lineage sorting.

Analysis of naturally hybridizing swordtail fish species reveals a mitonuclear genetic incompatibility among three genes that encode components of mitochondrial respiratory complex I, providing insights into the emergence of hybrid incompatibilities and reproductive barriers.

Species divergence in condensin regulation and centromere organization between the mice Mus musculus domesticus and Mus spretus drives chromosome decondensation and mis-segregation in their F₁ hybrid oocytes, reducing female fertility.

Three genomes must cooperate in plants — those in the nucleus, mitochondria and chloroplasts. Biparental inheritance of the nucleus and maternal inheritance of the organelles has made studying these interactions difficult. A new method allows the nucleus to be inherited paternally so the ‘black box’ of interactions can be studied.

High-throughput population genomics reveals how the evolution of chromosome arrangement and sequence divergence followed by secondary contact upon glacier retreat initiates homoploid hybrid speciation in natural populations of the budding yeast Saccharomyces paradoxus.