Gastro-oesophageal reflux disease articles from across Nature Portfolio

Gastro-oesophageal reflux disease is a condition in which contents of the stomach (gastric acid) flow back into the oesophagus, causing injury to the oesophagus and problematic symptoms such as heartburn or regurgitation. The condition usually arises as a result of dysfunction of the lower oesophageal sphincter.

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