Fungi articles from across Nature Portfolio

NKG2D is a central activating receptor know to recognise stress ligangs upregulated during cancer or infection. Here, Charpak-Amikam et al show that NKG2D also recognises fungal pathogens and plays a critical role in mounting an appropriate immune response to them.

Genome editing-mediated large-scale engineering, which modified 13 genes involved in multiple metabolic pathways, enabled us to develop a versatile filamentous fungal host highly-producing heterologous natural products.

Fusarium oxysporum f. sp. cubense tropical race 4 is threatening worldwide banana production. This study revealed a distinct evolutionary origin of tropical race 4 and how accessory genes and nitrosative pressure may have provided potential weaponries used by the pathogen to infect banana plants.

In this study, Diehl et al. report that brilacidin could be a promising antifungal drug against Cryptococcus neoformans.

Multi-drug resistance and virulence in Rhodosporidiobolus fluvialis, an emergent human fungal pathogen that causes fungaemia, is driven by body-temperature-induced elevated mutation rates.

Teresa O’Meara recounts her experience of approaching the emerging fungal pathogen, Candida auris, with an open mind, enabling her laboratory to uncover its unique biology.

This study shows that hyphae formation is critical for Candida albicans gut colonization in the presence of commensal bacteria owing to the production of a hyphal-associated factor.

In this study, Liu et al. explore the interplay between a fungal effector and a plant cysteine protease and design a small-molecule compound aimed at targeting this effector to combat rice blast disease.