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Fungal pathogenesis is the process by which fungi infect and cause disease in a host. Not all fungi are pathogens and have the ability for pathogenesis, also known as virulence.
Plant PR-1 proteins participate in defense responses against pathogens. Here, the authors show that PR-1-like proteins from the plant pathogenic fungus Ustilago maydis are important for virulence by detecting plant-derived phenolics and modulating plant PR-1-mediated defenses.
Fungal cell walls release β-1,3-glucan fragments that trigger plant immunity. Here, the authors show that a glucanase (Ebg1) of the blast fungus Magnaporthe oryzae suppresses plant immunity by hydrolyzing β-1,3-glucan. At the same time, Ebg1 induces plant immune responses that are dampened by a fungal protein that interacts with Ebg1.
The blast fungus Magnaporthe oryzae produces invasive hyphae in living rice cells during early infection. Here, the authors show that a fungal protein kinase promotes this biotrophic growth phase by coordinating cycles of autophagy and glutaminolysis in invasive hyphae.
This study shows that healthy individuals are reservoirs for genotypically and phenotypically diverse Candida albicans strains that retain their capacity to cause disease.
A recent paper in Nature describes how CRISPR-based engineering of wheat confers robust resistance to powdery mildew disease without negatively impacting crop growth and yields.