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Fungal genetics is the study of the mechanisms of heritable information in fungi. Yeasts and filamentous fungi are extensively used as model organisms for eukaryotic genetic research, including cell cycle regulation, chromatin structure, genetic recombination and gene regulation.
Development of a dual-fluorescent reporter system allows rapid quantification of diverse genomic copy number changes that arise in Candida albicans during adaptation to antifungal drugs.
Analysis of the conidial surface proteome of the fungal pathogen Aspergillus fumigatus and three closely related species reveals factors important for evasion and modulation of host immunity
Here, Lax et al characterise the role and distribution of an epigenetic mark, adenine methylation (6mA), in the genomes of early diverging fungi and find the enzymes that write symmetric and asymmetric 6mA in their DNA.
In this Journal Club, Amelia Barber discusses a study revealing intraspecies heterogeneity in a fungal pathogen, prompting us to re-evaluate the notion of ‘reference’ strains.
Identification and analysis of mutator strains in the human fungal pathogen Cryptococcus neoformans show that natural loss of RNA interference triggers massive accumulation of Cnl1 retroelements at subtelomeric regions.
Computational analysis of fungal genomes revealed that some early-branching fungi use selenocysteine, the selenium-containing amino acid, that was thought to be missing from proteins in this lineage.
