Follicular dendritic cells articles from across Nature Portfolio

Follicular dendritic cells (FDCs) are non-haematopoietic cells that are present in the B cell follicles of secondary lymphoid tissues. They carry intact antigens that are held on their surface for long periods in antigen–antibody complexes and are crucial for the selection of B cells that produce high-affinity antibodies.

Latest Research and Reviews

Reviews | 20 June 2014

Follicular dendritic cells: dynamic antigen libraries

Follicular dendritic cells (FDCs) in lymph nodes support the development of high-affinity antibody responses by retaining antigens at their cell surface for long periods of time. Although FDCs are generally regarded as 'accessory cells' in the germinal centre, recent data suggest that they have more active roles in the development of humoral immune responses. This Review focuses on our current understanding of FDCs.
- Balthasar A. Heesters
- , Riley C. Myers
- & Michael C. Carroll
Nature Reviews Immunology 14, 495-504
Research | 08 January 2014

Follicular dendritic cell secreted protein FDC-SP controls IgA production
- S Hou
- , I Landego
- & A J Marshall
Mucosal Immunology 7, 948-957
Research
01 February 2012 | Open Access

M cell-depletion blocks oral prion disease pathogenesis
- D S Donaldson
- , A Kobayashi
- & N A Mabbott
Mucosal Immunology 5, 216-225
Research | 22 October 2010

Follicular dendritic cell-induced microRNA-mediated upregulation of PRDM1 and downregulation of BCL-6 in non-Hodgkin's B-cell lymphomas
- J Lin
- , T Lwin
- & J Tao
Leukemia 25, 145-152
Reviews | 19 October 2010

B cell follicles and antigen encounters of the third kind
- Jason G Cyster
Nature Immunology 11, 989-996

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News and Comment

Research Highlights | 22 October 2021

Forget IL-4 to promote memory
- Laurie A. Dempsey
Nature Immunology 22, 1349
Research Highlights | 27 July 2012

FDCs — ubiquitous and ready for action

Follicular dendritic cells (FDCs) arise from ubiquitous perivascular PDGFRβ⁺cells.
- Ezzie Hutchinson
Nature Reviews Immunology 12, 617

All News & Comment

Follicular dendritic cells articles from across Nature Portfolio

Latest Research and Reviews

Follicular dendritic cells: dynamic antigen libraries

Follicular dendritic cell secreted protein FDC-SP controls IgA production

M cell-depletion blocks oral prion disease pathogenesis

Follicular dendritic cell-induced microRNA-mediated upregulation of PRDM1 and downregulation of BCL-6 in non-Hodgkin's B-cell lymphomas

B cell follicles and antigen encounters of the third kind

News and Comment

Forget IL-4 to promote memory

FDCs — ubiquitous and ready for action

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